Since Mastodon doesn't have an algorithm, hashtags are a way for folks to find others with similar interests. But if someone is just putting out spam, then that's another issue.
Sometimes I use weird hashtags as a joke or to make a point without really expecting anyone to search for those hashtags. It's not how they are supposed to be used, but I don't think it hurts anyone. (However, I'm open to changing my mind about that if someone has a good argument not to do that.)
And yes, putting the hashtags at the end rather the beginning is better for unsighted people so they don't have to sit through their screen reader saying "hashtag science hashtag earth hashtag bla bla bla" just to get to the actual toot.
Note: Having a lot of hashtags IS one of the signs of a spammer, but not necessarily a conclusive indicator.
@Pat
completion: ... and actually have nothing to say.
I'll open some exceptions. For now it's you and @jimdonegan
😉