"To characterize cell-type-specific transcriptional heterogeneity in active Crohn’s disease, we profiled 720,633 cells from the terminal ileum and colon of 71 donors with varying inflammation status."
#Immunology #MucosalImmunology #crohnsdisease
https://www.cell.com/immunity/fulltext/S1074-7613(23)00012-2
@cyrilpedia i think if we just keep increasing the total number of cells, the UMAPs shape will start resembling the organ they come from, right?
@dmaseda I think that hypothesis deserves funding!
@cyrilpedia
These papers are so important. Fabulous resource, especially given the challenges of getting these samples and costs of the single cell sequencing #crohnsdisease #immunology #IMMastodon #mucosalimmunology