"TREX1 normally degrades cytoplasmic DNA to prevent inappropriate innate immune activation by self DNA. Our mechanistic studies revealed that this same process functions during #influenza virus infection to enhance replication."

#immunology #Virology #InnateImmunity #Preprint #Trex1

https://www.biorxiv.org/content/10.1101/2023.02.07.527556v1?med=mas