"In this article, we show that HIV-infected human microglia express increased levels of TREM1 and are resistant to HIV-induced apoptosis. Moreover, upon genetic inhibition of TREM1, HIV-infected microglia undergo cell death in the absence of increased viral or proinflammatory cytokine expression or the targeting of uninfected cells."

#Infection #Immunity #Virology #HIV #Microglia

https://journals.aai.org/jimmunol/article/doi/10.4049/jimmunol.2300152/265707/HIV-1-Tat-Upregulates-TREM1-Expression-in-Human