When FTOC's aren't enough:
'Contrary to two-dimensional cultures, thymic epithelial organoids maintained thymus functionality in vitro and mediated physiological T cell development upon reaggregation with T cell progenitors. The reaggregates showed in vivo-like epithelial diversity and ability to attract T cell progenitors.'
#Immunology #Preprint #Organoid #Thymus
https://www.biorxiv.org/content/10.1101/2024.03.05.583513v1?med=mas