antipsychotic properties of cannabis compound CBD 

"[CBD] inhibited the binding of radio-domperidone … in the same biphasic manner as a dopamine partial agonist #antipsychotic drug such as aripiprazole… the dopamine partial agonist action of cannabidiol may account for its clinical antipsychotic effects."

ncbi.nlm.nih.gov/pmc/articles/

Schedule I drug in the USA, same as meth… unless you buy it in a pill called #Epidiolex.

#CBD #Cannabis #Meds #MedicalMarijuana #Schizophrenia #Bipolar #MentalHealth

antipsychotic properties of cannabis compound CBD 

Another choice quote from the paper:

"[T]wo recent reports
showed that 800 to 1000 mg of cannabidiol per day alleviated the signs and symptoms of schizophrenia…"

So, a gram of 100% #CBD a day, probably at the absolute cheapest where I live might run like $20-25 a day? Not positive. Prices continue to fall, though. And that's not taking into account potential bioavailability hacks.

Can't wait to see what this can do for bipolar disorder.

antipsychotic properties of cannabis compound CBD 

I just realized that this could explain the seemingly fantastical claim in my middle school health classes, based on ancient and dubious data, that smoking weed could lead to breast enlargement in men.

D2 antagonists or partial agonists can lead to gynecomastia as a side effect of the very action which produces their antipsychotic effect. Blocking D2 alters a feedback loop which regulates prolactin.

#pharmacology #psychopharmacology #drugs

Follow

@muninn It's very charitable of you to assume that high-school scaremongering about drugs would be based on a dubious studies in rats. I'd be inclined to assume that it was most likely made up on the spot. :)

Sign in to participate in the conversation
Qoto Mastodon

QOTO: Question Others to Teach Ourselves
An inclusive, Academic Freedom, instance
All cultures welcome.
Hate speech and harassment strictly forbidden.