Hao Yin @HaoYin@qoto.org

Modeling mammalian spermatogonial differentiation and meiotic initiation in vitro

An #OpenAccess T&R article from Oleksandr Kirsanov, Christopher Geyer and colleagues

https://journals.biologists.com/dev/article/149/22/dev200713/282465/Modeling-mammalian-spermatogonial-differentiation

This article is available under our Read & Publish Open Access initiative.
Researchers can find out about the benefits, read what researchers are saying and view a list of participating institutions at https://www.biologists.com/library-hub/read-publish/researchers/

#devbio #devbiol #ReadandPublish

Hi #ScienceMastodon. Have you already seen the latest post @preLights? 📜

https://prelights.biologists.com/highlights/arhgef18-participates-in-endothelial-cell-mechano-sensitivity-in-response-to-flow/

It has been written by #AarrenMannion #KarolinskaInstitutet who covers the #preprint from the lab of Anne-Clémence Vion working at the #InstitutThorax. In this work, the team of researchers show the importance of the guanine nucleotide exchange factor, ARHGEF18, in regulating endothelial cell alignment in the direction of flow. 🌊

#Biophysics #CellBiology #Endothelium #BloodFlow #Force

Hi #MedMastodon! 👋

#Introduction: I'm an #Endocrinologist at #Stanford, specializing in #Osteoporosis and #MetabolicBoneDisease. My lab studies #StemCells in bone 🦴 and the bone marrow microenvironment.

Some of my favorite topics: #WomenInMedicine #WomenInSTEM #PhysicianScientists #AAPI

I guess I should introduce myself #onhere: I am a postdoc in the Schier Lab at the Biozentrum (Switzerland). I am using #zebrafish to understand the #development of the nervous system. I love developmental biology of classic and non-canonical organisms, microscopy, loud music and comic books. Very much looking forward to meeting other scientists and cool people!
PS: I also help co-managing @ZebrafishRock , so make sure to give them a follow for the latest zebrafish community news

Issue 21 is complete!

On the cover is a 3D surface rendering of a lung lobe from a mouse #embryo, showing the relationship between the arterial network (red) and the lung epithelium (grey) from Chandrasekaran et al.

Also in Issue 21:
- 8 #Research Highlights
- In #preprints article on reconstituting the ovary
- Ruth Bellairs obituary
- 2 author interviews
- Poster & article on resolving #morphogenesis into quantifiable cell behaviours
- Nuclear movement Review

https://journals.biologists.com/dev/issue/149/21

Meet the #preLighters: Chee Kiang (Ethan) Ewe. 🌟

https://prelights.biologists.com/news/meet-the-prelighters-a-virtual-chat-with-chee-kiang-ethan-ewe/

Ethan is a #postdoc in the lab of @Odedrechavi at Tel Aviv University, Israel, where he studies the molecular basis of epigenetic #inheritance.

We spoke about his very international #career, the #mentors along the way, his future #goals, and the importance of #preprints both to him and the biological #community.

#Introduction #Interview #ECRs

Ooh another really interesting paper on #alzheimers and #lactadherin

Medin co-aggregates with vascular amyloid-β in Alzheimer’s disease

https://www.nature.com/articles/s41586-022-05440-3

A new #SpatialTranscriptomics technique was published on Cell! The authors used polony gels to capture the RNA in situ, and used pixel-seq to map #singlecell transcriptomes back to the tissue. Amazing experimental design! https://www.cell.com/cell/fulltext/S0092-8674(22)01367-8

BulkSignalR, a R package to infer ligand-receptor networks from bulk data including Visium #rstat #RNAseq #SpatialTranscriptomics
https://www.biorxiv.org/content/10.1101/2022.11.17.516911v1

scFates: a python package for pseudotime analysis from single cell data #scRNAseq #scATACseq #bioinformatics #python
https://academic.oup.com/bioinformatics/advance-article/doi/10.1093/bioinformatics/btac746/6832042

Welcome @karinayaniv ! I’m also just testing the waters here. I like it :) Slowly but surely finding all ours friends and colleagues! #science

Slides of my talk "An ABC of fluorescent proteins: Advances, Brightness and Considerations" presented at Symposium of the Microscopy Imaging Center (MIC) in Bern 2022 are available on Zenodo: https://doi.org/10.5281/zenodo.7341801

Told ya