Joram Mooiweer @JoramMooiweer@qoto.org

Now in #Science magazine (@sciencemagazine)

Katherine Freitas, Julia Belk, Ansu Satpathy, Crystal Mackall, & colleagues use #CRISPR screen to identify MED12 & CCNC as key regulators of human #TCell activation & function. Inactivation in #CART cells leads to increased T cell expansion, #metabolic fitness, & #tumor control!

bit.ly/Sci_abn5647

Be sure to also check out the accompanying Perspective by Caitlin Zebley & Ben Youngblood:

https://bit.ly/Sci_adf0546

#CancerImmunology #immunotherapy

#introduction I am an #immunologist at the #universityoftoronto. I study how our #mucosal immune system can influence our health, especially brain health. I love constructive discussions about science and how to make #academia a better place for everyone. I love #cooking, #gardening, #singing, #canoeing and learning from my 2 sons. Oh and my 3 @Cats too.