Julien Delpierre @JulienDelpierre@qoto.org

Hey, @elonmusk @Twitter @twittersupport or whoever is in charge: this was a service to a scientific community. If you goal is to drive away scientists from Twitter, you just got a step closer.
#Drosophila

The future of #multispectral #imaging (and very nice images!) If you are acquiring only 4 #channels in the #confocal, welcome to the future! @Nature Congrats to the authors! https://www.nature.com/articles/s41596-022-00739-x

From our current cover:
Dunn &co show that the coiled-coil protein mutated in colorectal cancer (MCC) localises to the centrosome in proliferating cells in intestinal crypts, and upon terminal differentiation, redeploys to non-centrosomal apical sites, mediated by phosphorylation of MCC by casein kinase 1δ and ε.
https://journals.biologists.com/jcs/article/135/21/jcs259272/278593/MCC-is-a-centrosomal-protein-that-relocalizes-to
#cellbiology #research #centrosome #intestinalcrypt

I feel like I didn’t get to see enough Nudibranchs this year. But can one ever see enough Nudibranchs? I did get to meet this beauty though. Goniodoris nodosa from #westruntonrockpools

#marinebiology #marinebiologyuk #northnorfolkcoast #northsea #sea #ocean #biology #rockpools #marinetaxonomy #wildlife #nature #intertidal #rockpools #rockpooling #seaslug #nudibranch

#introduction

Cell biologist, student of the #cytoskeleton, professor and dean at The Rockefeller University in #NYC.

Interested in #centrosomes, #cilia, and science #education, #outreach and #policy.

3,013 neurons, half a million synapses: the complete #connectome of the whole #Drosophila larval brain!

Winding, Pedigo et al. 2022. "The connectome of an insect brain" https://www.biorxiv.org/content/10.1101/2022.11.28.516756v1

We’ve mapped and analysed its circuit architecture, from sensory neurons to brain output neurons, as reconstructed from volume electron microscopy, and here is what we found. 1/

#neuroscience #connectomics #vEM #volumeEM

Hi Mastodon! I'm a journalist at @sciencemagazine, where I delve into stories about the scientific community and the various challenges that come with pursuing a career in science. I'm a former scientist myself—I earned a Ph.D. in ecology and did a stint as a postdoc before realizing that the best career path for me lay elsewhere. Feel free to get in touch if you'd like to introduce yourself or suggest a story idea. #ScienceMastodon #academicchatter

Hello #ScienceMastodon! I am an assistant professor in the MIT Department of Biology with our lab based at the Koch Institute. We build tools for high-throughput functional genomics in mice in order to understand and modulate regenerative capacity across mammalian tissues.

https://www.knouselab.org/

I do like it here on Mastodon, but the huge influx of people from Twitter means there are far fewer image descriptions than from even a couple of weeks ago. I’d love to tell every one of them about this, but quite frankly there are so many I don’t have the patience. I’d dearly love it if apps could block posts unless an image description was added to every photo, but I suppose that’s too much to hope for. I’m feeling really excluded from so many conversations. It’s getting as bad as Twitter.

Okay #introduction / #introductions time!!
My interests revolve around systems of subcellular organisation, from a #cellbiology and #biophysics perspective. I’m particularly focussed on #MembraneContactSites between organelles in funky cells like #neurons. I use a bunch of #microscopy techniques (#ElectronMicroscopy / #SuperResolution) alongside in vitro reconstitution systems to study contact site biology. The #EndoplasmicReticulum is the best organelle…this is a hill I am prepared to die on.

My first #toot on the woolly mammoth thing. I was rubbish at twitter, I'll probably be worse on Mastodon...but here are some neurons as a way of a premature apology :)

Our review on synthetic developmental biology is out
@ScienceMagazine
!

@GMartinezAra
and
@KStapornwongkul
discussed what developmental processes have been reconstituted/controlled so far and what tools/approaches will be the key in the next stages.

https://www.science.org/doi/10.1126/science.add9666

#introduction:
We are a new cell systems biology team at the #UniversityOfManchester #UoM.
We study #CellAdhesion #networks in health and disease, especially #cancer.
Fascinated by how adhesion proteins help #cells function in so many ways!

#proteomics #integrins #adhesion #cytoskeleton #nucleus #bioinformatics #omics #ExtracellularMatrix #ECM #NetworkBiology #DataViz

Still one of my favorite science music videos of all time. That and "The Molecular Shape of You" is some of the best sci-comms I have ever seen. Zero infantalization and rewarding on all levels.

#evodevo #scicomm #evolution

https://youtu.be/ydqReeTV_vk

Hi #ScienceMastodon. Have you already seen the latest post @preLights? 📜

https://prelights.biologists.com/highlights/arhgef18-participates-in-endothelial-cell-mechano-sensitivity-in-response-to-flow/

It has been written by #AarrenMannion #KarolinskaInstitutet who covers the #preprint from the lab of Anne-Clémence Vion working at the #InstitutThorax. In this work, the team of researchers show the importance of the guanine nucleotide exchange factor, ARHGEF18, in regulating endothelial cell alignment in the direction of flow. 🌊

#Biophysics #CellBiology #Endothelium #BloodFlow #Force

I guess I should introduce myself #onhere: I am a postdoc in the Schier Lab at the Biozentrum (Switzerland). I am using #zebrafish to understand the #development of the nervous system. I love developmental biology of classic and non-canonical organisms, microscopy, loud music and comic books. Very much looking forward to meeting other scientists and cool people!
PS: I also help co-managing @ZebrafishRock , so make sure to give them a follow for the latest zebrafish community news

"The great success of the AlphaFold programs poses the following questions: (i) What is the main reason for this success? (ii) What exactly do AlphaFolds do: prediction of the 3D protein structure based on its amino acid sequence and knowledge of the protein physics or recognition of this 3D structure, based on the similarity between some parts of its amino acid sequence and parts of sequences with already known 3D structures?"

#alphafold #preprint

https://www.biorxiv.org/content/10.1101/2022.11.21.517308v1?med=mas

Hi Everyone, I just switched server to @sciences.social. To re-introduce myself:

I’m a sociologist interested in transnational governance of scientific risks, especially in the realm of emerging life sciences. I am also interested in political participation and social movements relating to food, environment and citizen science.

Love cat, whisky, and Rembrandt.

#Introduction. #hellomastodon