Julien Delpierre @JulienDelpierre@qoto.org

#Cohesinopathy

BRD4 (acetyl lysine reader)-NIPBL (cohesin loading ) complex is critical to #NeuralCrest differentiation into #SmoothMuscleCell

BRD4 depletion->⏬#GenomeFolding+loop extrusion

BRD4 in #AorticAneurysm?

Dr. Rajan Jain lab Nature Genet 2021
https://www.nature.com/articles/s41588-021-00934-8

📣 I wrote a new post in my blog:
"Fixation of cells for imaging affects phase separation".
🔬 🍪

#imaging #microscopy #LLPS

https://greenfluorescentblog.wordpress.com/2023/02/25/fixation-of-cells-for-imaging-affects-phase-separation/

Speechless 💥💥💥
---
RT @erturklab
Imagine you could stain whole adult mice with standard IgG antibodies. What you couldn't do! We present wildDISCO technology for this🤗, creating the first whole body vascular, lymphatic, and nerve atlases. By @HongchengM @jieluo692 https://www.biorxiv.org/content/10.1101/2023.02.17.528921v1.full.pdf 🧵👇🏼(turn on the sound)
https://twitter.com/erturklab/status/1627615842073452544

Notch signaling in development and homeostasis

In their 'Development at a glance' article and poster, Oren Gozlan and David Sprinzak provide a brief overview of the Notch signaling and function in development and homeostasis

https://journals.biologists.com/dev/article/150/4/dev201138/287045/Notch-signaling-in-development-and-homeostasis

📣 We're thrilled to launch the first #AI4Life #OpenCall today! We offer #DeepLearning support to life #scientists who have unmet image analysis needs.

Apply now! https://ai4life.eurobioimaging.eu/first-open-call/

⏳Deadline: March 31, 2023

@EC_REA #AI #Bioimaging #Imaging #ImageAnalysis

An all-women team of four marine biologists, including #SFUBioSci prof Isabelle Côté @redlipblenny is preparing to row 5,000 km across the Atlantic Ocean in December, a journey that will take 40-60 days.

Their Salty Science voyage aims to raise $500,000 for three marine conservation organizations.
http://ow.ly/O9Ux50MPSM1 #biology #marinebiology #womeninscience #sfu

Today is #WomenInScience Day. I would like to thank all the great female scientists I have met. My first academic advisor in my undergraduate program was a female microscopist who sincerely cared about the impact of her research. She commercialized the first high resolution optical endoscopy system in China and is actively collaborating with biologists to discover new science. I was encouraged by her to pursue my PhD in the United States, which would be a life-changing experience for me.

Researchers @mpicbg, #mpipks & at the Center for Systems Biology Dresden show that mechanical structures within tubules that transport bile fluid could protect the whole tubular network against elevated pressure. Publication in@JCellBiol@mstdn.science by Maarten Bebelman, Matthew Bovyn from the labs of Marino Zerial and Pierre Haas. https://www.mpi-cbg.de/news-outreach/news-media/article/withstanding-the-pressure #cellbiology #mpicbg

Are you interested in cell adhesion, mechanobiology, cell signaling, morphogenesis or their relevance to development and disease? The 2023 Cell Contact and Adhesion Gordon Conference
is coming up June25-30 1/6
https://www.grc.org/cell-contact-and-adhesion-conference/2023/

Want to work at the intersection of morphometry and representation learning for bioimage analysis?

We have TWO open postdoctoral positions! Each comes with its own challenging biological question, unique dataset, and exceptional team of collaborators!

Details below👇

Hi #ScienceMastodon, time for an #introduction!

I'm an #EvoDevo biologist interested in how tissue #mechanics influences the #evolution of #morphogenesis. I study a deep and mysterious epithelial invagination that forms at the head-trunk boundary of #flies during #gastrulation, known as the #CephalicFurrow (see video below!). Currently, based in Germany as a postdoc in the Tomancak Lab at MPI-CBG. Looking forward to meeting you!

#DevBio #mechanobiology #microscopy #lightsheet #embryos

Interesting #preprint with a far-reaching conclusion: away from cell adhesions, #membrane-to-cortex attachment can regulate the #mechanics of #cells by changing the space available for #actin binders.

#biophysics #cellbiology

Together with the Zechner lab we have pushed live-cell quantitative lipid biochemistry to the single cell level. It works - but some lipids are weird. 🤓
Let us know what you think! https://www.biorxiv.org/content/10.1101/2023.01.27.525833v2

If you're hearing a lot about the fediverse these days, you should know: Mastodon is not the whole fediverse and the fediverse is not simply a Twitter replacement. The fediverse is an entire ecosystem, built on something called ActivityPub. Learn more: https://www.eff.org/deeplinks/2022/11/leaving-twitters-walled-garden

Hello everyone,

After digging a bit on Mastodon for the 1st time, I guess it’s time for a little #science #introduction.

I’m a postdoc at the #IBDM, where I am studying the effect of #oncogenes overexpressed in #hepatocellularcarcinoma.

Passionate by #CellBiology and #Cellcommunication, I studied #adhesivesmolecules function in #cellmigration and #cellinvasion in #pancreaticcancer during my PhD.

Always happy to discuss about #Actin #Cytoskeleton, #ECM remodelling & so many others things 🙃

Applications for the Embryology Course at the MBL Woods Hole are open! If you or someone you know wants to learn Developmental Biology from very cool people and get your hands on over 100 species (from sponges, jellyfishes, small worms, big worms, through fishes, frogs, chicken, or mice), apply! Scholarships are always available, lodging and food included. If you have any Q about it, reach out to me #DevBio #DevBiol #Embryology #Microscopy #CellBio #BlackInBio #FirstGen

https://www.mbl.edu/education/advanced-research-training-courses/course-offerings/embryology-concepts-and-techniques-modern-developmental-biology