Jon Lane @LaneLab@qoto.org

We also have a large number of fully funded PhD studentships available at the moment. Come join our incredible community of researchers and contribute to world-leading research in microbiology and structural biology. Please direct enquiries to the individual members of staff

DeepPROTACs is a deep learning-based targeted degradation predictor for PROTACs https://www.nature.com/articles/s41467-022-34807-3 #targetedproteindegradation

"MFN2 Q400 is the first known natural mitophagy- and shape change-defective MFN2 mutant. Its unique profile of dysfunction evokes mitophagic cardiomyopathy, suggesting a mechanism for its enrichment in clinical #cardiomyopathy."

#preprint #mitochondria

https://www.biorxiv.org/content/10.1101/2022.11.22.517462v1?med=mas

So it turns out there IS a tool to embed Mastodon timelines onto a website via HTML. You can find it here:

https://www.mastofeed.com/

Have just installed it here:

http://www.simonmarks.com/simonmarksfsn

...in place of the old #Twitter embed code. Works a charm!

@yoyoel @sdem21

Are you an #analytical #scientist based in the #UK? A new #PI who has a #data story to tell? I’m organising a webinar series and want to #invite #speakers to showcase how they look at #big #data. It can be #LCMS #GCMS #NMR other #spectroscopy or any #analytical #data. Interested? Drop me a toot! Pls #boost so I can cross servers and land into them all!

The lad Adrian Goldberg and myself will be dissecting the #wba ownership on the next podcast.

📰 "Lysosomes mediate the mitochondrial UPR via mTORC1-dependent ATF4 phosphorylation"
by 🔬 Li, T. Y., Wang, Q., Gao, A. W., Li, X., Mottis, A., Shong, M., Auwerx, J.
#bioRxiv #cellbiology http://biorxiv.org/content/10.1101/2022.11.14.516427v1?rss=1

Nice! Mastodon timeline feed by @idotj The codepen works a treat. I will look at embedding this for a couple of webpages soon. https://gitlab.com/idotj/mastodon-embed-feed-timeline

#job #fellowship #postdoc

Please help spread the news!

Open call for 3 #postdocs at the Konrad Lorenz Institute for Evolution and Cognition Research #KLI #KLIAustria

Theme: “Evolutionary theory in #interdisciplinary context”

https://kli.ac.at/content/en/the_kli/open_calls/view/10

#EvoMed #EvoBio #PublicHealth #EvoEco #Conservation #EvoNeuro #neuroscience #psychology #BioculturalEvolution #PhilSci #PhilBio #Histbio #EcoEcon #CulturalEvolution #KLIFellowships #EvoTheory #EvolutionaryBiology

Using a new advance in light microscopy, scientists can now observe proteins interacting and moving around inside living cells.
https://elifesciences.org/digests/76870/watch-this-papa

International Master´s Degree Programme in Biomedical Imaging - Call for applications for studies starting in September 2023 is opening soon!

What: #Master’s Degree Programme in Bio­medical Imaging

Where: #Turku, Finland

When: Apply during January 4-18, 2023 to study in autumn 2023

Duration of program: 2 years, 120 ECTS

opintopolku.fi

First in human trial of CRISPR edited neoantigen specific tumour infiltrating lymphocytes. NeoTCR-transgenic T cells were detected in tumour biopsies and toxicity mainly from lymphodepletion and CRS. Showed feasibility of using a neoantigen specific gene editing approach to TIL therapy
https://www.nature.com/articles/s41586-022-05531-1