Shai Bel @Mucus_Man@qoto.org

Welp

This broke my brain

https://journals.aai.org/jimmunol/article/196/4/1721/43258/A-Recombinant-G-Protein-Plus-Cyclosporine-A-Based

https://www.nature.com/articles/s41541-022-00591-w?utm_source=npjvaccines_etoc&utm_medium=email&utm_campaign=toc_41541_7_1&utm_content=20221227#Abs1

Cyclosporine A as a vaccine adjuvant to induce TRegs is something that would never have occurred to me, let alone it leading to *enhanced* antibody responses

Happy Festivus! #Science

Good morning, may your holiday meals be as bountiful as for this fox who just waltzed by

@cyrilpedia interesting!

last boost (#LB?): LOVED Carolyn @bertozzi's answer when asked for whether her winning the Nobel Prize provides "an enhanced platform" to address gender issues in STEM (at time 22:00): "It's probably a question that's better posed to the men around the table...there are so many more of them and they are in a position to make change that's 9 times greater than my own position." 🙌🏽🙌🏽🙌🏽

Our new must-read Nature paper: Inheritance of paternal DNA damage by repair restriction
We resolve one of the most long standing riddles in radiation biology: What are the heritable consequences of paternal radiation exposure? @CECAD @UniKoeln @dfg_public Find the answer here:
https://www.nature.com/articles/s41586-022-05544-w

What's the best way to debunk a misleading graph? 📊

A new study suggests that providing an "accurate alternative" is most effective.

Misleading graphs can omit baselines to exaggerate differences and cherry-pick sections of data to hide greater trends. The other methods tested included providing a warning arrow pointing to the issue or an educational or general text warning next to the graph.

https://doi.org/10.22323/2.21070207
#SciComm #ResearchIntegrity #Misinformation #Science @academicchatter

I made a few terrific friends on the bird site, but with the dislodging of the #covid #misinformation policy, the recent amplification of nutcases (who degrade #scicomm), I hope more scientist colleagues can share findings/thoughts/interesting papers here. #science #fediverse #twittermigration

https://www.nature.com/articles/d41586-022-04506-6

ICYMI: Inhibition of translation termination by Drosocin, an antimicrobial peptide from fruit flies.

https://www.biorxiv.org/content/10.1101/2022.12.11.519952v1

Key result, the authors find mutations in Drosocin that improve its ribosomal inhibitory activity, suggesting it could be improved further.

#Ribosome #antibiotics

My latest clinical pipeline column for Nature Medicine is a look at a drug recently approved by the #FDA to delay the onset of type 1 diabetes.

It's a direct descendant of the very first monoclonal ever approved for clinical use.

#Diabetes #Type1Diabetes #DrugDevelopment #DrugDiscovery #NatureMedicine #Immunology #MonoclonalAntibody

https://www.nature.com/articles/d41591-022-00115-y

With Twitter in tumult, @stokel@twitter.com looks at its influence on science communication, and what researchers will do next. Some are sticking it out on the site, others have already left.
https://www.nature.com/articles/d41586-022-04506-6

It is a new start for me on Mastodon. I am looking forward to slowly building my network here, and I hope to contribute to this community by sharing science from my group and others, and my 2 cents on various matters.

Hi.

The genetic and ecological landscape of plasmids in the human gut

https://www.biorxiv.org/content/10.1101/2020.11.01.361691v4?ct=

#bacteria #plasmids #microbiome

We preprinted a revised version of work by Carrie Zhu and colleagues, taking a new approach to understand sex differences in genetic effects on complex traits. Below are some of the revision highlights.

https://www.biorxiv.org/content/10.1101/2022.05.06.490973v1