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Fabrication uncertainty aware and robust design optimization of a photonic crystal nanobeam cavity by using Gaussian processes arxiv.org/abs/2402.09420 .optics .SP

Fabrication uncertainty aware and robust design optimization of a photonic crystal nanobeam cavity by using Gaussian processes

We present a fabrication uncertainty aware and robust design optimization approach that can be used to obtain robust design estimates for nonlinear, nonconvex, and expensive model functions. It is founded on Gaussian processes and a Monte Carlo sampling procedure, and assumes knowledge about the uncertainties associated with a manufacturing process. The approach itself is iterative. First, a large parameter domain is sampled in a coarse fashion. This coarse sampling is used primarily to determine smaller candidate regions to investigate in a second, more refined sampling pass. This finer step is used to obtain an estimate of the expected performance of the found design parameter under the assumed manufacturing uncertainties. We apply the presented approach to the robust optimization of the Purcell enhancement of a photonic crystal nanobeam cavity. We obtain a predicted robust Purcell enhancement of $\overline{F}_{\mathrm{P}} \approx 3.3$. For comparison we also perform an optimization without robustness. We find that an unrobust optimum of $F_{\mathrm{P}} \approx 256.5$ dwindles to only $\overline{F}_{\mathrm{P}} \approx 0.7$ when fabrication uncertainties are taken into account. We thus demonstrate that the presented approach is able to find designs of significantly higher performance than those obtained with conventional optimization.

arxiv.org

Online Mean Estimation for Multi-frame Optical Fiber Signals On Highways arxiv.org/abs/2402.09423 .data-an .SP

Online Mean Estimation for Multi-frame Optical Fiber Signals On Highways

In the era of Big Data, prompt analysis and processing of data sets is critical. Meanwhile, statistical methods provide key tools and techniques to extract valuable insights and knowledge from complex data sets. This paper creatively applies statistical methods to the field of traffic, particularly focusing on the preprocessing of multi-frame signals obtained by optical fiber-based Distributed Acoustic Sensing (DAS) system. An online non-parametric regression model based on Local Polynomial Regression (LPR) and variable bandwidth selection is employed to dynamically update the estimation of mean function as signals flow in. This mean estimation method can derive average information of multi-frame fiber signals, thus providing the basis for the subsequent vehicle trajectory extraction algorithms. To further evaluate the effectiveness of the proposed method, comparison experiments were conducted under real highway scenarios, showing that our approach not only deals with multi-frame signals more accurately than the classical filter-based Kalman and Wavelet methods, but also meets the needs better under the condition of saving memory and rapid responses. It provides a new reliable means for signal processing which can be integrated with other existing methods.

arxiv.org

Weakly Supervised Detection of Pheochromocytomas and Paragangliomas in CT arxiv.org/abs/2402.08697 .IV .CV

Weakly Supervised Detection of Pheochromocytomas and Paragangliomas in CT

Pheochromocytomas and Paragangliomas (PPGLs) are rare adrenal and extra-adrenal tumors which have the potential to metastasize. For the management of patients with PPGLs, CT is the preferred modality of choice for precise localization and estimation of their progression. However, due to the myriad variations in size, morphology, and appearance of the tumors in different anatomical regions, radiologists are posed with the challenge of accurate detection of PPGLs. Since clinicians also need to routinely measure their size and track their changes over time across patient visits, manual demarcation of PPGLs is quite a time-consuming and cumbersome process. To ameliorate the manual effort spent for this task, we propose an automated method to detect PPGLs in CT studies via a proxy segmentation task. As only weak annotations for PPGLs in the form of prospectively marked 2D bounding boxes on an axial slice were available, we extended these 2D boxes into weak 3D annotations and trained a 3D full-resolution nnUNet model to directly segment PPGLs. We evaluated our approach on a dataset consisting of chest-abdomen-pelvis CTs of 255 patients with confirmed PPGLs. We obtained a precision of 70% and sensitivity of 64.1% with our proposed approach when tested on 53 CT studies. Our findings highlight the promising nature of detecting PPGLs via segmentation, and furthers the state-of-the-art in this exciting yet challenging area of rare cancer management.

arxiv.org

Leveraging cough sounds to optimize chest x-ray usage in low-resource settings arxiv.org/abs/2402.08789 -bio.QM .AS .AI .LG

Leveraging cough sounds to optimize chest x-ray usage in low-resource settings

Chest X-ray is a commonly used tool during triage, diagnosis and management of respiratory diseases. In resource-constricted settings, optimizing this resource can lead to valuable cost savings for the health care system and the patients as well as to and improvement in consult time. We used prospectively-collected data from 137 patients referred for chest X-ray at the Christian Medical Center and Hospital (CMCH) in Purnia, Bihar, India. Each patient provided at least five coughs while awaiting radiography. Collected cough sounds were analyzed using acoustic AI methods. Cross-validation was done on temporal and spectral features on the cough sounds of each patient. Features were summarized using standard statistical approaches. Three models were developed, tested and compared in their capacity to predict an abnormal result in the chest X-ray. All three methods yielded models that could discriminate to some extent between normal and abnormal with the logistic regression performing best with an area under the receiver operating characteristic curves ranging from 0.7 to 0.78. Despite limitations and its relatively small sample size, this study shows that AI-enabled algorithms can use cough sounds to predict which individuals presenting for chest radiographic examination will have a normal or abnormal results. These results call for expanding this research given the potential optimization of limited health care resources in low- and middle-income countries.

arxiv.org

Infinite-horizon optimal scheduling for feedback control arxiv.org/abs/2402.08819 .SY .SY

Infinite-horizon optimal scheduling for feedback control

Emerging cyber-physical systems impel the development of communication protocols to efficiently utilize resources. This paper investigates the optimal co-design of control and scheduling in networked control systems. The objective is to co-design the control law and the scheduling mechanism that jointly optimize the tradeoff between regulation performance and communication resource consumption in the long run. The concept of the value of information (VoI) is employed to evaluate the importance of data being transmitted. The optimal solution includes a certainty equivalent control law and a stationary scheduling policy based on the VoI function. The closed-loop system under the designed scheduling policy is shown to be stochastically stable. By analyzing the property of the VoI function, we show that the optimal scheduling policy is symmetric and is a monotone function when the system matrix is diagonal. Moreover, by the diagonal system matrix assumption, the optimal scheduling policy is shown to be of threshold type. Then we provide a simplified yet equivalent form of the threshold-based optimal scheduling policy. The threshold value searching region is also given. Finally, the numerical simulation illustrates the theoretical result of the VoI-based scheduling.

arxiv.org
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