Andrew Kennard @askennard@qoto.org

'Story is now so valued that, in many realms, it has become compulsory—consider the recitations required of asylum seekers or rape victims, who are penalized or dismissed if the parameters of their stories do not readily conform to the genre.
And if a story betrays us? The solution, it seems, is to cast about for a better one.'

https://www.newyorker.com/magazine/2023/07/10/seduced-by-story-peter-brooks-bewitching-the-modern-mind-christian-salmon-the-story-paradox-jonathan-gottschall-book-review

New lab paper! Bio-protocol from @NFerrandiz

3D Ultrastructural Visualization of Mitosis Fidelity in Human Cells Using Serial Block Face Scanning Electron Microscopy (SBF-SEM)

https://bio-protocol.org/e4708

#CellBiology #Imaging #VolumeEM

Did you now...? That multi-well plate lids stack and seal nicely so that they can be re-used to store (oily) microscope slides in between? You're welcome 😉 #don'twastewaste

Our paper is out in
Current Biology
🎉🎉
Congrats Sushila & co-authors!

Read more to find out how an oncogene impacts mitotic substrate attachment leading to out-of-plane cell divisions:

https://www.cell.com/current-biology/fulltext/S0960-9822(23)00723-6

Do you have coding skills and some familiarity with Python programming? Join our online course on Deep Learning for Microscopy Image Analysis! #DL4MIA

Bring your own microscopy datasets for hands-on learning on image denoising and restoration, image segmentation, failure cases and limitations, with practical insights from experienced trainers.

Register by 4 August 👉 https://humantechnopole.it/en/trainings/ht-deep-learning-for-microscopy-image-analysis-2023/

#sciencemastodon #science #ai #python #humantechnopole #deeplearning #imageanalysis

With @florianjug

@WXFanatic @mappingsupport @ai6yr

Hey, let's be subject to the whims of a DIFFERENT erratic reactionary billionaire!

'Here, we show that yeast paralogous genes are more divergent in transcription than in translation. We explore two causal mechanisms for this predominance of transcriptional divergence: an evolutionary trade-off between the precision and economy of gene expression and a larger mutational target size for transcription.'

https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010756

Transferred #mitochondria accumulate reactive oxygen species, promoting proliferation. #Cancer #ReactiveOxygenSpecies #CellCycle https://elifesciences.org/articles/85494?utm_source=mastodon&utm_medium=social&utm_campaign=organic

This makes me physically sick. It’s a toxic brew of the artificial scarcity of ‘elite’ institutions, the cheapening of research, and the runaway professionalization of being a kid.

https://www.propublica.org/article/college-high-school-research-peer-review-publications

I wrote this little program to visualise biological tracking data from #microscopy. We used it a lot for sense checking and verifying a lot of our data, but sadly it won't make it into our next paper. Anyway, today I tidied it up a bit and will make it available with all the rest of the code for others to use.

#reproducibility #CellBiology #ScienceMastodon

I respect screaming babies on airplanes because they're the only ones providing honest feedback about the overall air travel experience

Six year ago, I returned to NIH in Bethesda, where I started my career as a science writer, to be a patient in an ambitious study to understand the patho-biology of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

The study included 30+ researchers & many substudies, and was essentially a fishing expedition to understand what goes wrong to make us so sick (like bedbound-for-years sick). 1/

(photo by @Bether )

#MEcfs #ChronicIllness #medicine #nih

Democrats being sunk on judicial appointments (one of the few areas where the party can take tangible, meaningful action) because an aged member of the party can't physically make it to any of the votes but also refuses to simply treat her situation with grace and resign is such an apropos thing for where the country is right now. The arguments against Feinstein's resignation are so dumb as to verge on bad faith.

https://www.sfgate.com/politics/article/dianne-feinstein-resign-calls-arguments-17910730.php

please enough video tutorials give me a webpage with text and pictures

Amazing how many brilliant scientists will look at an LLM "passing" a standardized test and think, "wow, this computer is very smart" and not "standardized tests are very bad at measuring intelligence"

Getting a lot of new follower requests from folks with zero bios. Please fill out bios or do a short intro. It helps a lot. Thanks ✌

Beware of anti-myths!

Spinach *does* have a higher concentration of iron than a steak.

The problem is that it's not absorbed nearly as much when digested.

Nice read.

What next? Edge (23,34) is not really ambiguous in the Karate Club?

Crosspost from @DanLarremore@twitter.com:

New one on my list of favorite papers.

"Academic Urban Legends"

It explores the ironic follies of how we cite literature by tracing a myth: that we think spinach has a lot of iron only because of a decimal point error in the early 1900s. h/t @jugander@twitter.com

https://journals.sagepub.com/doi/10.1177/0306312714535679

🐦🔗: https://twitter.com/DanLarremore/status/1631481816057257985