"Taken together, beyond revealing the central role of cristae architecture to prevent mtDNA release and inflammation, our results mechanistically link mitochondrial cristae disorganization and inflammation, two emerging hallmarks of aging and aging-related degenerative diseases."

#mitochondria #inflammation #InnateImmunity #Immunology

He et al @CellReports

https://www.cell.com/cell-reports/fulltext/S2211-1247(22)01657-6