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'Recently, more than 100 novel #antiviral prokaryotic systems were uncovered (2–7). Among them, multiple bacterial antiviral systems were identified as the evolutionary origin of eukaryotic antiviral proteins, including CBASS (homolog of the eukaryotic cGAS/STING pathway), gasdermins, viperins or Avs (related to the NLR family) (8–12). In this work, we explore whether novel eukaryotic immune components can be identified by homology with prokaryotic defense systems.'
@cyrilpedia cool!