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This is such an important point in the comparative study of Toll like receptors and immunity across taxa: the prototypical Toll is *not* a microbial/foreign pattern recognition receptor, it is only activated by a host molecule.

"The Drosophila Toll receptor differs from the mammalian TLRs in that the Drosophila Toll receptor functions as a cytokine receptor (reviewed in Ref. 5), whereas the mammalian TLRs recognize foreign structures directly and thus are pattern recognition receptors (PRRs)."

journals.aai.org/jimmunol/arti

@cyrilpedia I'd call it a cytokine receptor, which I find endlessly amusing

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