IL6 is not always the bad guy.
"In the penumbrae of human stroke brain lesions, we identified a subpopulation of microglia that express vascular endothelial growth factor A. These cells, termed ‘repair-associated microglia’ (RAMs), were also observed in a rodent model of CVI and coexpressed interleukin (IL)-6Ra. Cerebrovascular repair did not occur in IL-6 knockouts or in mice lacking microglial IL-6Ra expression"
#Immunology #Inflammation #Microglia #Neuroimmunology
@cyrilpedia ...carrying coals to Newcastle..
@cyrilpedia Bringing the term "immune contexture" from #cancer #immunology to #Immunology....well...not surprising...