Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
“I was forty-five years old and tired of being an artist. Besides, I owed $20,000 to relatives, finance companies, banks, and assorted bookmakers and shylocks. It was really time to grow up and sell out, as Lenny Bruce once advised.”
Mario Puzo (in Leave the Gun, Take the Cannoli)
#Books #Book #writer #reader #bookshelf #bookstodon
'Here, we used a human tonsil organoid platform to elucidate the cellular dynamics of Ag-reactive B and T cells in primary human tonsils as they responded to IIV, LAIV, and #influenza viruses. Tonsil organoids are a useful system for tracking human adaptive immunity and can recapitulate numerous aspects of the developing B and T cell response'
#Immunology
https://www.cell.com/immunity/fulltext/S1074-7613(23)00276-5
My new Clinical Pipeline column is out in Nature Medicine.
It's on JAK inhibitors for alopecia - and at the black box safety warning the FDA attached to this entire class of drugs.
'Here, we used CRISPR-based loss-of-function screens to identify a markedly limited set of ISGs that confer interferon-mediated suppression of a model alphavirus, Venezuelan equine encephalitis virus (VEEV). We show via combinatorial gene targeting that three antiviral effectors—ZAP, IFIT3, and IFIT1—together constitute the majority of interferon-mediated restriction of VEEV, while accounting for < 0.5% of the interferon-induced transcriptome.'
My new Clinical Pipeline column is out today in Nature Medicine, a look at JAK inhibitors for alopecia - and at the black box safety warning the FDA attached to this entire class of drugs.
The story of the current generation of anti-obesity drugs from early failures with leptin & ghrelin told by one of its pioneers, Matthias Tschöp. A new podcast project, you can listen to "#Obesity is a brain disease" by scrolling down at the link below.
https://www.pioneercampus.org
#science #metabolism #neuroscience #sciencecommunication #sciencepodcast #scicomm
Madalena & Jorge, the secret identity of @thehunchbacksociety revealed.
#Art #Ceramics #Stoneware #ArtGallery #Pottery #artists #artmastodon
If you're off on vacation soon, you can mine this episode of the #EMBOPodcast for reading tips, as Pavel Tomancak suggested some of his favorite Czech #SciFi authors
Now I have to go see this:
"Kate McKinnon plays a damaged doll cruelly nicknamed Weird Barbie"
https://www.ft.com/content/4efa2465-1045-4dc3-97ad-4b8e91a718e4
The story of the current generation of anti-obesity drugs from early failures with leptin & ghrelin told by one of its pioneers, Matthias Tschöp. A new podcast project, you can listen to "#Obesity is a brain disease" by scrolling down at the link below.
https://www.pioneercampus.org
#science #metabolism #neuroscience #sciencecommunication #sciencepodcast #scicomm
“The knowledge content of scientific theories has been interpreted as restricted to the ability to give predictions. In this way, in my opinion, we lose sight of science’s ability to subvert and widen our vision of the world.”
- Carlo Rovelli, “Anaximander and the birth of science”.
#Books #Book #Bookshelf #Reader #ScienceBooks #SciComm #bookworm #bookstodon
“Map 7 & 8. The la Motte-Husson Portolan (Mayenne, France, 17th Century)
If, as Arthur Robinson wrote in his Elements of Cartography, “maps are to be looked at while charts are to be worked on”, then portolans are the quintessential charts, navigational guides that do not wrestle with other aspects of representation. The Margrave was ecstatic when he acquired the la Motte-Husson Portolan, believing that it would finally allow him to contribute to the defense of the nation. Over time a confusing series representing the same location emerged, with shifting sailing directions. Exhaustive archival investigation revealed that the Baglion de la Dufferie family had the series of prints made to mark the different routes used by the toy sailboats of the Dauphin (the future Louis XIII) to cross the moat of their home in Mayenne, the Chateau de la Motte-Husson. This discovery made thirty years after the series was acquired precipitated a severe depression – it was the reason von Willebrand chose to recuperate in the Kaiserslautern spa where he ultimately expired.”
https://madalenaparreira.com/SPAM
#Print #Prints #Printmaking #CopperPrint #CopperEtching #Etching #Handmade #Art #Cartography #ArtGallery #artmastodon
The American Museum of Natural History is one of my favourite places - it was great to visit again, crowds & all. When we lived in New York, I was a volunteer at the museum - I recommend the program to anyone living in the city (you don't have to be a scientist, in my group there was everything from lawyers to bodega owners).
The story of the current generation of anti-obesity drugs from early failures with leptin & ghrelin told by one of its pioneers, Matthias Tschöp. A new podcast project, you can listen to "#Obesity is a brain disease" by scrolling down at the link below.
#science #metabolism #neuroscience #sciencecommunication #sciencepodcast #scicomm
At the #metropolitanmuseumofart
"Jim Gagnon American In the Metropolitan Museum of Art, 1958-59
Gelatin silver print
Gift of the artist, 1960 (60.506.7)
The photographer Jim Gagnon was an astute observer of a museum visitor's physical condition as they became absorbed in artworks. At a time when The Met forbade cameras in the galleries, Gagnon surreptitiously followed museum goers and captured their meanderings, pauses, and poses."
From Madalena Parreira's relief etchings on copper (1999-2006).
#Prints #Print #printmaking #printmakingart #printmaker #etching #artgallery #artmastodon
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
