Thiago Carvalho @cyrilpedia@qoto.org

A protein known as Pericentrin may contribute to intellectual disability in individuals with Down syndrome by disrupting signaling hubs that control how cells grow and develop. https://elifesciences.org/digests/78202/the-cell-biology-of-down-syndrome?utm_source=mastodon&utm_medium=social&utm_campaign=organic

Beautiful review indeed.
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RT @NatureRevCancer
And the moment you've all been waiting for... Our top downloaded article in 2022: CRISPR in cancer biology and therapy by @alynakatti @biancaaadiaz @cmcaragine @nevillesanjana & @dow_lab http://go.nature.com/33Rgp4Y @NatResCancer #CRISPR #NRCtop10of2022
https://twitter.com/NatureRevCancer/status/1618974859370938369

@cyrilpedia @CoriBargmann
Wonderful episode! Recommended to all. Cori’s wisdom always astounds me. Sample of a few wide ranging gems:

Cori’s PhD work led to a cancer treatment.

The notion that the human genome project was a ‘Rosetta stone’ for comparing genes across species.

Worms with their 302 neurons only have 20K genes. We with our billions neurons only have 30K genes.

The big idea that what’s sets humans apart from other species is our ability to communicate and pass along knowledge - we each do not have to invent arithmetic

The latest episode of the #EMBOPodcast is live & (in my biased opinion) this should make for some great weekend listening.
@CoriBargmann & I discussed the evolution of behavior, #OpenScience, a worm’s sense of smell, the Human #Brain Initiative, mentorship, and much more.

You can listen to it at the link below or your preferred podcast app

#neuroscience #Celegans #oncogenes #sciencepolicy #mentorship #SciComm #SciencePodcast

https://www.embo.org/podcasts/our-special-feature-as-humans-is-communication/

Madalena made this illustration for a piece I wrote about Charles Lindbergh, who designed a perfusion pump for organ transplantation and published it in JEM 1935.
https://madalenaparreira.com

#HistoryScience #HistoryOfScience #ScientificIllustration

https://rupress.org/jem/article/62/3/409/4051/AN-APPARATUS-FOR-THE-CULTURE-OF-WHOLE-ORGANS

I have moved from fediscience.org so here's my #introduction again 😬!
I am a #paleobotanist and a #CNRS researcher in Montpellier, France. I study #fossils from the #Paleozoic and early #Mesozoic (400 to-200 million years ago) to understand the #evolution of plant diversity and biology 🌿⛏️ I'm also interested in plants that are still living (#iamabotanist) and will post about #paleobotany and #botany 🌳🌺

https://blog.cartoonmovement.com/2023/01/editorial-cartoons-and-ai.html

A nice study of #LassaFever in #Guinea by @stephanie200586 and colleagues. https://wwwnc.cdc.gov/eid/article/29/2/21-2525_article

Found evidence that fractured habitats are associated with increased exposure.

Seroprevalence up to 59% but so few clinical cases reported from Guinea. <20 in 10 years. 🤔

Elusive glass octopus spotted in the remote Pacific Ocean. Only its eyes, optic nerve and digestive tract are opaque. This rarely-seen glass octopus bared all recently — even a view of its innards — when an underwater robot filmed it gracefully soaring through the deep waters of the Central Pacific Ocean. Image credit: Schmidt Ocean Institute

Powerful images do often become media echoes. This media echo started in 1545 on a #broadside and shows the #Reformation in a nutshell. It was reprinted and variated into the seventeenth century. Sometimes the print was colored to sell for a higher price. #histodons

What makes this image special? You see Pope Paul III holding a flaming papal bull, belching forth sulphur, and the audience is farting towards him, shouting: Here are the lips made to measure for the foot of the Pope.

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