next up to read: really interesting new work by @marionpepper lab
already thinking how we might integrate this into what we learned from Gaya/Milpied labs showing IL4 promotes more permissive GC and "bystander" memory B cells in the tissue
IL-4 downregulates BCL6 to promote memory #Bcell selection in germinal centers | bioRxiv
RT @AdaptiveImmuni2@twitter.com
Happy to share our newest (and oldest) study. I started this project in 2012 as a postdoc with Ed Palmer. It is the last paper with data I generated with my own hands in Ed's lab (part of Fig.1). I will guide you through the data in the thread. https://tinyurl.com/yv4a8ec6 1/10
🐦🔗: https://twitter.com/AdaptiveImmuni2/status/1619038246599819264
"In the early 2000s, a series of groundbreaking studies began revealing yet another facet of that mystery — the way mushrooms respond to sound, despite having no auditory organs."
https://www.themarginalian.org/2022/11/13/mushrooms-sound-waves/
"We set out to systematically investigate global sequencing databases for a signature of #molnupiravir #mutagenesis. We find that a specific class of long phylogenetic branches appear almost exclusively in sequences from 2022, after the introduction of molnupiravir treatment, and in countries and age-groups with widespread usage of the drug."
#Preprint #COVID19 #Covid #Antiviral #SARSCoV2
https://www.medrxiv.org/content/10.1101/2023.01.26.23284998v1
Senior Scientist/Instructor in Cancer Biology and Tumor Microenvironment @subhamoy_d
Come join us in #Buffalo at #Roswell Park as a #SeniorScientist
#ScienceJobs #job #cancerbiologyjobs
Buffalo #UnitedStatesUS #Researcher...
https://jobrxiv.org/job/roswell-park-comprehensive-cancer-center-27778-senior-scientist-instructor-in-cancer-biology-and-tumor-microenvironment/?feed_id=35620
On Tuesday I had the pleasure of moderating a great panel on #longcovid with Akiko Iwasaki, Carmen Scheibenbogen, Michael Edelstein and Marc Lecuit. The video is up here now for anyone who wants to catch up on it:
@Sneuroble
Check out the academics on mastodon list!
https://github.com/nathanlesage/academics-on-mastodon
In particular, there's psychology and neuroscience lists of people to follow.
Neuroscience: https://docs.google.com/spreadsheets/d/1k3Q0LOewgIAJolbf-7XagK0twnpjeoyl2uLxR5U80vo/
Psychology: https://kaitclark.github.io/mastodon-psychology/
(no stats list alas)
I like to follow the neuroscience@a.gup.pe group as well for neuroscience.
Some related instances to check out:
neuromatch.social (neuro)
synapse.cafe (neuro)
sciences.social (social science)
bayes.club (Bayesian statistics)
sigmoid.social (machine learning)
RT @haesleinhuepf@twitter.com
🚨Job alert🚨
If you're interested in interdisciplinary research between Imaging, #BioImageAnalysis and Machine Learning, join us as PhD student in #BioImageDataScience for understanding Human Pathomechanisms via @digsbb@twitter.com @PoLDresden@twitter.com
🔬🖥️🧠🚀
https://www.digs-bb.de/fileadmin/user_upload/downloads/phd-projects/2023-01-phd-project-bia.pdf
🐦🔗: https://twitter.com/haesleinhuepf/status/1618974060138094592
A board of scientific advisors voted today to recommend strengthening the government's oversight of research on potential pathogens. Here's my story with Ben Mueller https://www.nytimes.com/2023/01/27/science/biosecurity-virus-pathogens-covid-lab-leak.html
"Using a novel multi-cell type, human induced pluripotent stem cell (hiPSC)-derived lung organoid (LO) system, validated against primary lung cells, we found that inflammatory cytokine/chemokine production and #interferon (IFN) responses are dynamically regulated autonomously within the lung following #SARSCoV2 infection, an intrinsic defense mechanism mediated by surfactant proteins"
A primer to directed #evolution: current methodologies and future directions -
https://pubs.rsc.org/en/content/articlelanding/2023/cb/d2cb00231k
💥 New preprint out today
We conclusively demonstrate that mutational events caused by molnupiravir treatment can be seen in globally sequenced SARS-CoV-2 genomes, in some cases with onwards transmission.
🧵
https://www.medrxiv.org/content/10.1101/2023.01.26.23284998
Madalena made this illustration for a piece I wrote about Charles Lindbergh, who designed a perfusion pump for organ transplantation and published it in JEM 1935.
https://madalenaparreira.com
#HistoryScience #HistoryOfScience #ScientificIllustration
https://rupress.org/jem/article/62/3/409/4051/AN-APPARATUS-FOR-THE-CULTURE-OF-WHOLE-ORGANS
@NicoleCRust That's an interesting thought, thanks. This is a much better space for storytelling - there were some epic threads on the Other Site, but they were the exception.
#Creativity as an antidote to research becoming too predictable
In this #openaccess commentary, Markus Baer, Anja Groth, Anders Lund & Katrine Sonne-Hansen argue why risk-taking and blue-sky research needs to be actively fostered in budding scientists
Cf. #NightScience concept of M. Lercher and @itaiyanai
How can we address the research gap between reproductive health and disease and other areas of research? https://elifesciences.org/articles/75061?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Don’t miss your chance to apply at IMPRS-BI! Stand out with your application and become part of our brand-new graduate school. We offer doctorates in a wide range of life sciences in an international and highly innovative research environment.
Make the last days count and apply now: https://imprs-bi.mpg.de/
#science #phd #phdingermany #imprs #maxplanck #maxplanckinstitute #phdposition #phdprogram
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com