Thiago Carvalho @cyrilpedia@qoto.org

FYI

"And while a human fatality is yet to be recorded, the experience of being stung can be excruciating. Keith Payne, a recipient of the Victoria Cross (the nation’s highest military award), has said that being stung by a platypus was worse than being struck by shrapnel."

https://www.nybooks.com/articles/2023/02/23/monotreme-dreams-platypus-matters-jack-ashby/

'In this Review, we give an overview of the regulation and cancer relevance of major metabolic pathways in which acetyl-CoA participates. We further discuss recent advances in understanding acetyl-CoA metabolism in normal tissues and tumours and the potential for targeting these pathways therapeutically.'

#Metabolism #cancer

https://www.nature.com/articles/s41568-022-00543-5

"The grip of financial self-interest in US health care is becoming a stranglehold, with dangerous and pervasive consequences. No sector of US health care is immune from the immoderate pursuit of profit, neither drug companies, nor insurers, nor hospitals, nor investors, nor physician practices."

HT @gregggonsalves

https://jamanetwork.com/journals/jama/fullarticle/2801097

"Library warfare hit record highs during the pandemic. The American Library Association logged 729 attempts to censor resources in 2021, targeting 1,597 books, the most since the ALA started tracking requests more than two decades ago. Last year was set to exceed that total, the association says."

https://www.ft.com/content/dea4318c-6ecc-4dbd-8952-1ee025061a47

Great lamb & yoghurt recipe from Ottolenghi's "Simple". Bonus: it actually is simple - unlike most of his recipes, it does not require that you live next to a souk dreamed up by Italo Calvino for one of his invisible cities.

#Books #foodbooks #cookbooks

Experience shows that you need the big stick.

"Researchers say that the document is an ambitious effort to address searing inequities that occurred during the pandemic, but that it doesn’t do enough to force countries to share scarce resources or punish those that don’t comply."

https://www.nature.com/articles/d41586-023-00358-w

"Establishing that Neanderthals hunted elephants is interesting, although it should not be shocking. What is impressive is the sheer quantity of meat seemingly fully exploited by Neanderthals at Neumark-Nord 1. Straight-tusked elephants were huge: Females weighed 6 tons and males up to 13 tons."

https://www.science.org/doi/10.1126/sciadv.adg6072

Colograph of book cover by Madalena

"The works presented here are created with alternative materials rather than etched on copper. From squashed paper costumes to packaging and leather book covers, objects are inked with different processes, both intaglio and planographic."

https://madalenaparreira.com/Colographs

"Illumina sharply increased its spending on lobbying over the past two years as it tried to build support against antitrust regulators in the US and Europe that have attempted to block its $8bn acquisition of cancer testing company Grail."

https://www.ft.com/content/5298eddf-8ddb-49e5-ad20-df5c2021a053

"Our findings demonstrate that ApoE4-expressing astrocytes acquire distinct transcriptional repertoires at single-cell and spatially-resolved domains, which are driven in-part by preferential utilization of the cRel transcription factor."

#Preprint

https://www.biorxiv.org/content/10.1101/2023.02.06.527204v1?med=mas

'Through riveting and braided profiles of Lee Krasner, Elaine de Kooning, Grace Hartigan, Joan Mitchell, and Helen Frankenthaler, Gabriel illustrates in this groundbreaking group biography how New York City supplanted Paris as the modern art capital of the world in the 1940s and ’50s.'

https://www.theatlantic.com/books/archive/2023/02/art-writing-books-recommendation-list/672947/