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Rosalind Franklin, born in 1920, was a British chemist whose contributions were vital to the discovery of the structure of DNA. Her work led to the Nobel Prize being awarded to two men, Watson and Crick, who allegedly stole her work and never acknowledged her contribution. #WomensHistoryMonth

"The neonatal Fc receptor and the planet Neptune share the distinction of having had their existence predicted by theoretical models before they were discovered."

My latest Clinical Pipeline column at Nature Medicine is out.

nature.com/articles/d41591-023

Sounds exciting.
"...positive feedback between cell state and signalling pattern regulates the long-range signal coding that drives morphogenesis."
Controlling periodic long-range signalling to drive a morphogenetic transition doi.org/10.7554/eLife.83796

@cyrilpedia Freakonomics did a 3 episode deep dive inti Adam Smith - highly recommended!

Here is a link to part 2; it is most relevant to your post.

podcasts.apple.com/us/podcast/

Issue 4 is complete!

On the cover: Xenopus neurula stained for Sox3 protein. For more details see the Research article by Horr et al.

journals.biologists.com/dev/ar

Also in Issue 4:
- Research Highlights on neurodevelopment, muscle and tongue epithelium
- @p_r_francois Editorial on theoretical biology
- Author interview with Rana Fetit & David Price
- Mayssa Mokalled interview
- Notch signaling poster
- Fertility Primer

journals.biologists.com/dev/is

Hey! Come to Lisbon! It's going to be a lot of science fun!
---
RT @J_Cell_Sci
Join us in Lisbon this May and hear Francesca Bottanelli @fran_bottanelli speaking on "Investigating cellular logistics with live-cell STED super-resolution microscopy"#celldyn2023

Find out more and register at
biologists.com/meetings/celldy
twitter.com/J_Cell_Sci/status/

Anna-Maria Jürgensen @ajuergensen, author of some lovely papers on computational neuroscience in #Drosophila is here: welcome!

"A neuromorphic model of olfactory processing and sparse coding in the Drosophila larva brain" iopscience.iop.org/article/10.

"Prediction error drives associative olfactory learning and conditioned behavior in a spiking model of Drosophila larva" biorxiv.org/content/10.1101/20

"A realistic locomotory model of Drosophila larva for behavioral simulations" biorxiv.org/content/10.1101/20

RT @OBCBioimaging
Looking for an exciting job in bioimaging? Then look no further and join us @OBCBioimaging! We are recruiting a light microscopy specialist to help support the day to day running of our world-class light and electron microscopy facility. jobs.ac.uk/job/CXS675/light-mi

Almost 200 million people around the world have endometriosis. So why does it take so long to get diagnosed? Here's an #EndometriosisAwarenessMonth thread about this common and chronic gynaecological condition.

Harald Hess awarded the 2023 James Prize in Science and Technology Integration by the US National Academy of Sciences: nasonline.org/programs/awards/

At #HHMIJanelia, the lab of Harald Hess revolutionized electron microscopy with enhanced FIBSEM (C. Shan Xu et al. 2017 @eLife elifesciences.org/articles/259 ) –now in use by us at #MRCLMB, and applied for whole #Drosophila CNS imaging; built an automated STEM to image the whole #Drosophila larval body at 5x5x35 nm; and so much more. Hats off! Congratulations!

Spoiler alert: no (Smith was not a moral idiot).

"How did this happen? How did Smith’s ideas become so thoroughly integrated into conservative defenses of the free market against regulation? And are these the only ways of reading his work?"

newrepublic.com/article/170242

Preprint: gene fusions in amyotrophic lateral sclerosis.

"We leveraged bulk RNA-Seq data from human post-mortem samples to determine whether fusion events occur in ALS. We report for the first time the presence of gene fusion events in several brain regions as well as in spinal cord samples in ALS."

medrxiv.org/content/10.1101/20

FInd joy where you can:

"To the delight of scientists across the life sciences, reads, which are the output of sequencing instruments, have been getting longer."

nature.com/articles/s41592-022

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