Thiago Carvalho @cyrilpedia@qoto.org

#Hypothalamic menin protects against aging in mice. #menin expression drops during aging; mimicking this decrease induces premature #aging phenotypes, while restoring menin in aged mice ameliorates cognitive & systemic features of aging #PLOSBiology https://plos.io/3YPbMyE

My science outreach take on our work mapping and analyzing the #connectome of the #Drosophila larval brain, this time in catalan:
https://blocs.mesvilaweb.cat/cardona/el-cervell-per-a-que/?vlw=1

#CadaDiaCiència #català #ciència

If you found the above ☝️ study eye-opening, consider that Deer Tick/Powassan Virus (POWV) may persist in the brain, as studied in this new paper:

"Of Murines and Humans: Modeling Persistent Powassan Disease in C57BL/6 Mice"
https://doi.org/10.1128/mbio.03606-22

😲 Specifically, the authors found that the #virus may persist in the brain without creating infectious particles, just as non-infectious measles can persist in the brain indefinitely — and be fatal:
https://pubmed.ncbi.nlm.nih.gov/6879001/
#virology #ViralPersistence

#Findsfriday! Amphorae from the shipwreck at Albenga. It’s one of the largest known #Roman cargo ships. Over 1200 amphorae (type Dressel 1B) have been raised, the estimated load was around 10,000 amphorae. The type of container was predominantly used to transport #wine, each had a capacity of ca. 25 l, which would be the equivalent of a cargo of ca. 250,000l of wine!
The shipwreck dates back to the first half of the 1st century AD.

Photo: Museo Navale in Albenga

#RomanArchaeology #archaeology

"There was a very strong influence of the computational biology community that was already used to sharing code and the concept of open source code was not at all novel."
#EMBOPodcast

@tlemberger on the creation of the first #OpenAccess at EMBO, @MolSystBiol

https://www.embo.org/podcasts/a-steppingstone-to-an-open-science-future-embo-press-moves-to-full-open-access/

Women weren't allowed to major in genetics when Barbara McClintock attended Cornell, so she earned her PhD in botany instead.

Working on the chromosomal activity of maize in the '40s and '50s, she discovered genetic transposition, proving that genes turn physical characteristics on and off.

Initially met with skepticism, her work was confirmed in the '60s and '70s; she won the Nobel Prize in Physiology or Medicine in 1983.

#WomensHistoryMonth

https://www.energy.gov/articles/five-fast-facts-about-barbara-mcclintock

graphic: Cort Kreer

This image is absolutely awesome: a bacterium being attacked by bacteriophages (viruses that infect bacteria). For once in biology, they look EXACTLY LIKE the pictures in the textbooks!

You can even see that some phages have injected their DNA because their ‘body’ is lighter!
---
RT @sci_bastian
That's the reason I love #electronmicroscopy
You can see cool stuff like this :D

Any ideas what's going on here?
https://twitter.com/sci_bastian/status/1636138908814651396

What is a "predatory publisher" anyways?

in http://bit.ly/WhatPredPub I polled folks for their opinion of various publishing groups (blue poll)🤔

Rate of IF/SJR can correlates with public opinion (🎻plot)

I repolled 1 year later (black poll), broadening and confirming trends ✅

In http://bit.ly/1yrPredPub I introduce the terms "Rent-seeking behaviour" and "Vampire Press" to better define... what is a "Predatory Publisher" anyways?💸 🧛‍♂️

For #OpenScience
#AcademicChatter #PredatoryPublishing

“The nature of biological training is changing” Could not agree more - fascinating episode of the #EMBOpodcast with the chat between Thiago Carvalho and StephenQuake on quantitative va qualitative, basic vs applied research. A must listen 😊 https://open.spotify.com/episode/2QjGkVgxQM1OgS3mPfvi7d?si=HpY8G4AXR1K2RxG9EWuUHw

Wow! Single cell transcriptomics reveals taste buds in the oesophagus!

https://www.science.org/doi/10.1126/sciadv.add9135

#PaperThemeTune "Taste-Buddy Holly" by Weezer
https://www.youtube.com/watch?v=Kjr7US2Z9aY

From peacocks to penguins, stunning 200-year-old French illustrations of exotic, endangered, and extinct birds https://www.themarginalian.org/2023/03/16/la-galerie-de-oiseaux/

Historians write for public audiences and for specialist audiences. Just as important as the former, the latter's really, really important, too. Thanks to @bencarp for reminding me about this piece I wrote for #ScholarlyKitchen some years ago! #Evergreen #history #histodons https://scholarlykitchen.sspnet.org/2016/01/27/the-importance-of-academic-history-writing/