Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
Thanks to @marcdionne for arranging an authentically grey & wet London experience.
It was a pleasure discussing the science behind the development of RNA vaccines with his students at Imperial.
Thiago Carvalho
boosted
we discussed this below paper from @vscooper on our journal back in 2019 (here is the link: https://onlinelibrary.wiley.com/doi/abs/10.1111/mec.15307), which was online just in time to motivate our setup, e.g. longer intervals of certain plant in the alternating environment, instead of alternating host each cycle
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RT @EvolvedBiofilm
Story started by Chris Blake (MSc thesis) under the supervision of @MathildeNordga1, where we want…
https://twitter.com/EvolvedBiofilm/status/1637061757574299651
Thiago Carvalho
boosted
In this #house lives the #Blue.
There is no #deadend without an exit for it.
#street #streetphotograpjy #architecture #urban #urbanscape #sky #bluesky #photography #photodons
@schoppik @NicoleCRust I'm sorry the toot provoked a somatic response.
@Rahimilab To me, it makes sense at the repertoire level, at least from the perspective that if you are part of the same social group, you are likely to have some overlap in the universe of antigens, commensals and pathogens you encounter (and transmit within group).
Hanuman inspired ceramics by @hunchbacksociety
#ceramics #handmade #ceramic #stoneware #handmade #ArtMastodon
"We tracked behavior of rewilded laboratory mice of three inbred strains in outdoor enclosures and examined contributions of behavior, including social associations, to immune phenotypes. We found that the more associated two individuals were, the more similar their immune phenotypes were. Social association was particularly predictive of similar memory T and B cell profiles and was more influential than sibling relationships or worm infection status."
https://www.biorxiv.org/content/10.1101/2023.03.15.532825v1?med=mas
This feels like it deserves a drum roll
"But to solidify the case for the hypothetical protoribosome, Yonath and her laboratory would have to build it."
@schoppik @NicoleCRust
That's interesting, I read her initial toot a bit differently, as one level removed: the job or practice of understanding the scientific job or practice :)
@NicoleCRust (thanks)
I agree - it's a word that probably sends more scientists running for the hills than even philosophy (but closer to what you're getting at, I think).
I wish I had one! To me it also involves an aesthetic component, what it means for a paper or an experiment not just to be important, but "beautiful" (classic examples here are Meselson and Stahl & Luria-Delbruck).
'The World Health Organization said data from China suggesting Covid-19 arose from animals in Wuhan’s wet market should have been shared with the world three years ago, adding that the findings “do not provide a definitive answer” as to the origin of the virus.'
https://www.ft.com/content/939ed85a-2d07-4e11-a3a9-8781f802174f
Thiago Carvalho
boosted
Chef's kiss
"That is surely worth it just to preserve the lovely Icelandic word for computer: tölva, meaning number prophetess."
https://www.ft.com/content/262542a7-6616-4f4e-87b0-d0e39b27727f
Thiago Carvalho
boosted
'Recent studies have highlighted the value of using ancient genomes from different epochs, known as aDNA time series, to reconstruct the evolutionary history of immune disorders and past epidemics'
Thiago Carvalho
boosted
In a recent commentary in Nature Reviews Molecular Cell Biology, @Odedrechavi & Pavel Tomancak present some ideas on how to credit the work of co-authors on publications - essentially how to figure who did what, now that it is not unheard to see papers with three or more joint first authors (and senior authors as well).
https://www.nature.com/articles/s41580-023-00587-x
The issue matters, of course, for research assessment and career progression. Bernd Pulverer and Thomas Lemberger discussed some alternatives beyond simple authorial credit, making use of emerging #OpenScience tools. You can listen to our conversation at the link below.
#EMBOPodcast
Thiago Carvalho
boosted
Looking for a word to describe a slice of meta-science:
I'm looking for a word for that slice of science that discusses how we should go about doing science. I'm talking about the realm that is often offered up in what scientists often call "think pieces", "opinions", and "perspectives".
Because few would call the stuff of think pieces 'philosophy', philosophy of science" isn't the right term, but the notion is definitely overlapping with that field.
I think of it as an an arm of 'metascience', but that word itself is an umbrella term that refers to many things (like reproducibility and incentive structures for scientists).
#HasokChang coined the term "complementary science" to refer to the study of history to inform how we should do science; that's too specific.
Do you know of an existing word for this?
How does "perspective science" strike you?
@NicoleCRust Epistemology of science may come close?
Thiago Carvalho
boosted
New free Open Source book, with Paul Thompson, on Evaluating What Works. Intended as a primer on methods for evaluating interventions for those with little background in statistics and research methods. Examples are from speech and language therapy.
https://bookdown.org/dorothy_bishop/Evaluating_What_Works/
"The concept of reviewing preprints is catching on in the life sciences. At least two dozen preprint-refereeing initiatives of various sizes have been launched in the past few years. The largest (apart from eLife itself) is @ReviewCommons, launched in December 2019 by the California-based non-profit organization @ASAPbio and @EMBOPress."
The title of this AP piece summaries the situation in Portugal quite well.
"Simoes and many others, increasingly including the middle class, are being priced out of Portugal’s property market by rising rents, surging home prices and climbing mortgage rates, fueled by factors including the growing influx of foreign investors and tourists seeking short-term rentals."
https://apnews.com/article/portugal-housing-crisis-lisbon-tourism-6e9e08c136b6dc98bf5cb51292c0f27b
@PLOSBiology Very interesting work - the FDA has just granted breakthrough status to a menin inhibitor (in a subset of leukaemia patients)
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
