Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
BIOINFORMATICIAN Immunology @neoviral
Come join us in #NYC as a #Bioinformatician to study Transposable Elements
#ScienceJobs #job
New York City #UnitedStatesUS #Bioinformatician
https://jobrxiv.org/job/mount-sinai-school-of-medicine-27778-bioinformatician-immunology-2/?feed_id=37791
Thiago Carvalho
boosted
There's an amazing job opportunity at U of Maine to become the director of the Darling Marine Center. https://umaine.hiretouch.com/job-details?jobID=80356&job=director-of-the-darling-marine-center
'Two weeks after the last dose, antibodies to P. falciparum circumsporozoite protein and PfSPZ were higher in protected versus unprotected vaccinees. A three-dose regimen of PfSPZ Vaccine demonstrated safety and efficacy against malaria infection in malaria-experienced adults.'
#Immunology #Malaria #InfetionImmunity #vaccine
https://www.science.org/doi/full/10.1126/scitranslmed.abj3776?af=R
@BLMG A foto e' antiga, aviso quando for hora do update!
'Molecular glue degraders are defined as the compounds leading targeted protein degradation (TPD) by creating novel ligase-substrate interactions. Here, we identified AK59 as a novel molecular glue degrader for STING.'
'Determined to catch up, Japan is ramping up a 1.1 trillion yen ($8.5 billion) initiative that aims to give Japan the capability to develop a vaccine for a new virus in 100 days, a goal being adopted by many countries.'
Thiago Carvalho
boosted
Work from the group employing analysis of large datasets to identify recurrent sequences and public CD8 TCR clones associated with durable responses to #cancer immunotherapy in patients with #melanoma. #immunology #cancer #oxford
https://www.biorxiv.org/content/10.1101/2023.02.11.528080v1
Public health in 21st century America.
"Mississippi’s woes are an acute example of a larger public health failure that is reprised nearly every time a major health threat grabs headlines. The problem, experts say, is that Congress starves state and local health agencies of cash for even basic needs in quiet times."
https://www.nytimes.com/2023/02/13/us/politics/covid-public-health-departments.html
"We children of the Boomers went into the workplace with a double expectation – we wanted a proper occupation, and we wanted it to be a vocation. And once again, science seemed to fit the bill."
@TIR_scienceblog
https://totalinternalreflectionblog.com/2023/02/12/science-vocation-to-professionto-job/
Thiago Carvalho
boosted
New posting! This asks whether #science #careers in #academia have evolved from a hobby, to a #vocation, to a profession...and maybe now into a job (and how that's probably a good thing).
Funnily, when I first conceived of this posting (quite a way back) I thought it would be a negative one about how people don't care enough any more, but that has almost completely turned around - I now think it's a good thing if people are stepping back. A good #work/life_balance isn't something to whine about - we should be insisting on it.
Anyhows, read the posting and see what you think... ;-)
https://totalinternalreflectionblog.com/2023/02/12/science-vocation-to-professionto-job/
Thiago Carvalho
boosted
The Bibliographical Society of America is seeking to build an endowment to support the Dorothy Porter Wesley Fellowship. The Fellowship of $3,000 is awarded each year to a Black individual for research on any topic. Thanks to a gift from Lisa Unger Baskin, the fund is halfway to its goal of $85,000, but it needs our help to make it the rest of the way. https://bibsocamer.org/support-bsa/porter-endowment-fund/
Thiago Carvalho
boosted
London calling.
---
RT @Raw_News1st
#MadridSeLevanta12F
Huge demonstration in Madrid. More than 250,000 people demonstrate to defend the public health system and protest against its privatization.
https://twitter.com/Raw_News1st/status/1624778873744261122
For the "every cell is an immune cell" files:
'In this Essay, we present fibroblasts as not only the builders and renovators of tissue environments but also the rheostat cells for immune circuits. Although they perform location-specific functions, they do not have badges of fixed identity'
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001954
"Know less" seems generous:
'The Big Con of the book’s title is not a crime; it’s a confidence trick. Consultancies and outsourcers, Mazzucato argues, know less than they claim, cost more than they seem to, and — over the long term — prevent the public sector developing in-house capabilities.'
https://www.ft.com/content/fb1254dd-a011-44cc-bde9-a434e5a09fb4
Measuring antibodies in the murine central nervous system.
"In our study, we standardized a procedure and statistical analysis for a highly sensitive ELISA of a mouse Ab in mouse (C57BL/6J) CNS tissue."
Thiago Carvalho
boosted
#Portugal : au moins 4 815 victimes de pédocriminalité dans l’Eglise depuis 1950 Plus de 500 témoignages ont été entendus par le groupe d’experts au cours de ce travail étalé sur environ un an. https://www.liberation.fr/international/europe/portugal-au-moins-4-815-victimes-de-pedocriminalite-dans-leglise-depuis-1950-20230213_JGU6SMRWGZHBLIWKL5PYWZ7ZUM/?utm_medium=Social&utm_source=Mastodon
Thiago Carvalho
boosted
Some good recent finds for #academics on mastodon. :)
- Mastodon Media List: https://docs.google.com/document/d/1TTtXbf0yDXHKXwR9jpZ4kU79mmiZT5KIM7U4tBr83hY/edit#heading=h.m7f2jiwk8u11- list of Academic Journals and News Outlets.
- TrueSciPhi.org: https://truesciphi.org/ - Various comprehensive #science, #philosophy, and #mathematics lists covering podcasts, Mastodon, and Twitter.
- and of course: Academics on Mastodon - https://nathanlesage.github.io/academics-on-mastodon/
Thiago Carvalho
boosted
New from my Crick colleagues in @jpvincentlab: Ecdysone functions as a morphogen to control proliferation vs growth arrest in wing disc
Striking parallel with how bifunctional Gli proteins mediate Shh morphogen responses
https://www.biorxiv.org/content/biorxiv/early/2023/02/11/2023.02.10.527985
Thiago Carvalho
boosted
Interesting review about the role of sialic acids in interactions with gut microbes. Sialidases, transporters and metabolic enzymes particularly discussed.
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
