"Follicle cells triggered by hair movements release the neurotransmitters histamine and serotonin, chemical messengers linked to biological phenomena as varied as inflammation, muscle contraction and mood changes."
https://www.nytimes.com/2023/11/08/science/hair-follicle-neuron-touch.html
'Varias universidades árabes pagan hasta 70.000 euros anuales por cabeza a reputados científicos extranjeros para que mientan y declaren en una base de datos que su lugar de trabajo principal está en Arabia Saudí.'
"SARS-CoV-2 infection is milder in children, but the underlying mechanisms are not fully understood. This study finds increased interactions between immune and epithelial cells in children's noses, priming the epithelium for stronger interferon responses upon infection."
Magalhães et al @emboreports
A while back we asked you, the Node community, to vote for your favourite artwork from @BSDB #DevBio_Art exhibition — the results are now in!
Have a look at the People's and Judges' choices of #microscopy images and #SciArt work:
https://thenode.biologists.com/peoples-choice-and-judges-choice-from-the-bsdb-the-node-virtual-art-exhibition/
The exhibition is still open until the end of November! Have a stroll around:
🔬Scientific images
https://artspaces.kunstmatrix.com/node/12245599
🖼#SciArt and 'Art by scientists'
https://artspaces.kunstmatrix.com/node/12245684
🦞🐬🐢🐤Historic embryo zoo
https://artspaces.kunstmatrix.com/node/12186775
Austrian Actress Hedy Lamarr (Hedwig Eva Maria Kiesler) was born #OTD in 1914 (not 1913).
At the beginning of World War II, she and avant-garde composer George Antheil developed a radio guidance system for Allied torpedoes that used spread spectrum and frequency hopping technology to defeat the threat of jamming by the Axis powers. Though it was never used in wartime, this device is a component of present-day satellite and cellular phone technology. via @wikipedia
Fast alignment of mass spectra in large proteomics datasets, capturing dissimilarities arising from multiple complex modifications of peptides - BMC Bioinformatics https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-023-05555-y
---
#proteomics #prot-paper
"A team of researchers backed by Alzheimer’s Research UK and the Alzheimer’s Society have launched a £5m project to trial simple blood tests in the NHS, with the hope of speeding up diagnosis and reaching more people. They aim to be able to determine whether someone has the disease using a single drop of blood."
The immune landscape of murine skeletal muscle regeneration and aging
"...challenge established notions on immune regulation of skeletal muscle regeneration, providing a new set of potential targets to improve skeletal muscle health and regenerative capacity in aging.".
https://www.biorxiv.org/content/10.1101/2023.11.07.565995v1.full.pdf+html
"What we are focused on now is the expansion of biological specificity. Modern quantitative biology has great instrumentation to measure how things work physiologically, but that needs really specific readouts; if the reagent that you are using is not specific enough, then your assay probably won't be very good."
"Tuberculosis, which is preventable and curable, has reclaimed the title of the world’s leading infectious disease killer, after being supplanted from its long reign by Covid-19. But worldwide, 40 percent of people who are living with TB are untreated and undiagnosed, according to the World Health Organization."
https://www.nytimes.com/2023/11/06/health/tuberculosis-tb-treatment-vaccine-diagnosis.html
"The Covid inquiry has shown us that inside No 10 there was a combination of squabbles, chaos and incompetence best described as an absurdist tragedy. The obvious takeaway is, “don’t elect someone like Boris Johnson”"
‘The analysis estimates that 1.5–2% of all scientific papers published in 2022 closely resemble paper-mill works. Among biology and medicine papers, the rate rises to 3%."
Thanks to LS4FUTURE Associated Laboratory for the invitation to speak at Career Day 2023 - and to hear the other panelists's stories. As a side note, it was odd to learn from postdocs at the speed-dating portion of the afternoon that Portugal's government had fallen (as if they needed *more* uncertainty).
(Photo by Andreia Freitas/IBET)
#Cichlids and other fish species you definitely don't have in your #aquarium.
From the understudied region of Northern #Zambia being situated between two African Great Lakes: Lake #Tanganyika and Lake #Malawi.
Schedel et al. 2023
https://www.sciencedirect.com/science/article/pii/S0380133023002381
Selective macroautophagy of the #EndoplasmicReticulum (ER) and the #nucleus, known as ER-phagy and nucleophagy respectively, are poorly understood. A study in #FissionYeast reveals that conserved ER-shaping protein Yep1 (REEP1-4 ortholog) is required for these processes; in its absence, #ERphagy/#nucleophagy cargo structures accumulate in the cytoplasm #PLOSBiology https://plos.io/464ZfuI
How does #CorrectiveFeedback influence subsequent choices? This computational study reveals that humans don't consider such feedback as a reward for value but as evidence to learn about the statistical structure of a perceptual task, offering a principled account of the historical effects in both directions of time #PLOSBiology https://plos.io/46bc0nk
DIR PRMS AND REG AFFAIRS
Moffitt Cancer Center
See the full job description on jobRxiv: https://jobrxiv.org/job/dir-prms-and-reg-affairs/?feed_id=64816
#ScienceJobs #hiring #research
Tampa #UnitedStatesUS #Director #ProjectManager #Scientist
https://jobrxiv.org/job/dir-prms-and-reg-affairs/?feed_id=64816
'One frustrated modeller observed a lack of ethnic and gender diversity among scientists recruited to Sage, and a failure to stress-test assumptions; one Downing Street adviser, a rarity for having attended a state school, lamented that these missing perspectives created “problems in decision-making, policy development and culture”.
https://www.ft.com/content/4c378024-c3ec-4171-a0e6-4c5ad159336e
"The Brazilian authorities, however, say it was something far more sinister: a meeting of the Hammerskins, a neo-Nazi group founded in Dallas in 1988 that they say has recently found its way thousands of miles south, to Brazil’s most starkly conservative region, reflecting a surge in far-right extremists in Latin America’s largest nation."
https://www.nytimes.com/2023/11/07/world/americas/brazil-neo-nazis-extremism.html
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com