Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
'The results of these efforts were extraordinary, however. The images revealed jumping spiders, weevils, dragonfly nymphs, and myriad other arthropods in exquisite detail, from an unprecedentedly personal perspective.'
Thiago Carvalho
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'Neste aspeto, a Fundação para a Ciência e a Tecnologia (FCT) e os diferentes ministros que a têm tutelado adicionam à sua já conhecida incompetência uns laivos de crueldade, uma vez que nem dão estabilidade laboral aos investigadores, nem lhes dizem o que têm de fazer para a obter. Os investigadores vivem com o credo na boca, impossibilitados de fazer planos de vida além de seis anos ou a fazê-los por sua conta e risco, confiando não no seu trabalho e mérito individual, mas na sorte de serem selecionados num qualquer concurso.'
https://www.publico.pt/2024/07/11/ciencia/opiniao/investigadores-senhor-ministro-2096580
Thiago Carvalho
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'It would be easier to run sensible immigration policy with EU freedom of movement. Better to have migrants with good employment rights who can respond to shifting demand by switching employers and moving back and forth from the UK rather than vulnerable workers trapped by company- or sector-specific visas. It’s unlikely the UK would be flooded with cheap European labour: incomes in central and eastern European countries have rapidly converged with those in western Europe. But anything related to the EU and free movement of workers remains toxic. Depressingly, Labour this year ruled out the European Commission’s suggestion of an EU-UK youth mobility scheme.'
https://www.ft.com/content/a0e9fe66-5ca1-4fbc-af7a-6cbbe4f1da1d
Thiago Carvalho
boosted
I'm trying to finish up everything before my holiday starts next week, but the #SeaIce is continuing to break up so now we have to organise collection of the buoys probabaly within the next couple of weeks.
Unfortunately, it's pretty cloudy right now, and we seem to be missing some sentinel1 scenes, so we're very much relying on our local collaborators to judge
Update on latest post:
http://sternaparadisaea.net/2024/07/08/breaking-up-is-hard-to-do/
'The tool — a type of ‘base editor’ — modified the target gene in more than 90% of an Escherichia coli colony inside the mouse gut. “We were dreaming of being able to do that,” says Xavier Duportet, a synthetic biologist who co-founded Eligo Bioscience, a biotechnology company in Paris. The findings were published today in Nature.'
'The findings suggest that i) the Romans most likely discovered the islands around the 1st century BCE; ii) Berber groups from western North Africa first set foot on one of the islands closest to the African mainland sometime between the 1st and 3rd centuries CE; iii) Roman and Berber societies did not live simultaneously in the Canary Islands; and iv) the Berber people rapidly spread throughout the archipelago.'
Thiago Carvalho
boosted
Priming lymphocyte responsiveness and differential T cell signaling in pediatric IBD patients with Cannabis use. https://www.biorxiv.org/content/10.1101/2024.07.08.602495v1?med=mas
'Patients develop T cell lymphomas after CAR-T therapy extremely rarely — less than 0.1% of the time, Rejeski said. Second cancers also rarely cause death in CAR-T patients, Rejeski said. Mortality from these subsequent cancers occurs roughly 0.5% of the time. In comparison, infections led to the deaths of about 4% of CAR-T patients in a study that Rejeski published in Nature Medicine this week. “Infections, infections, infections. This is the main driver of non-relapse mortality,” he said.'
https://www.statnews.com/2024/07/12/cancer-car-t-therapy-fda-secondary-cancers/?utm_campaign=rss
Thiago Carvalho
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Host-use Drives Convergent Evolution in Clownfish and Disentangles the Mystery of an Iconic Adaptive Radiation https://www.biorxiv.org/content/10.1101/2024.07.08.602550v1?med=mas
Thiago Carvalho
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Thiago Carvalho
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Abstract submission now open for the 2024 online Big Team Science conference! @btscon.bsky.social
https://bigteamscienceconference.github.io/
#metascience We (https://contributorshipcollaboration.github.io/ , https://neuromatch.social/@tenzingContrib) are working on a hackathon proposal ,"Helping big teams give more CRediT to their contributors" :)
Thiago Carvalho
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Gen X seems to have a higher cancer risk than older generations. Here are some disturbing graphics and the latest ideas about what could be contributing to this trend https://www.scientificamerican.com/article/gen-x-faces-higher-cancer-rates-than-any-previous-generation/
'These studies have helped to answer “some of the questions that were precipitated by the FDA announcement,” Maus said. They still have not found definitive evidence that CAR-T therapy has directly caused new cancers, she said, and scientists continue to suspect that such an event would be extremely rare.'
#Immunology #Immunotherapy #CARTcells
https://www.statnews.com/2024/07/12/cancer-car-t-therapy-fda-secondary-cancers/?utm_campaign=rss
Thiago Carvalho
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Open Research Europe: An Update https://www.openaire.eu/open-research-europe-an-update
Thiago Carvalho
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'The problem is not that young people are eco-anxious. It's that people in positions of power are not'
Climate activist Clover Hogan founded non-profit Force of Nature to help young people turn feelings of climate anxiety into action. She says that climate anxiety is not a negative phenomenon, rather a healthy psychological response. It is evidence that “we’re awake in a culture that tries to numb us and switch us off from the climate crisis.”
Thiago Carvalho
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Cytosol-living Trypanosoma cruzi amastigotes scavenge cholesterol from host ER and Golgi complex https://www.biorxiv.org/content/10.1101/2024.07.10.602841v1?med=mas
Thiago Carvalho
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Amino acids trigger MDC-dependent mitochondrial remodeling by altering mitochondrial function https://www.biorxiv.org/content/10.1101/2024.07.09.602707v1?med=mas
Thiago Carvalho
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Septins function in exocytosis via physical interactions with the exocyst complex in fission yeast cytokinesis https://www.biorxiv.org/content/10.1101/2024.07.09.602728v1?med=mas
'Far from the Bastille, at the Clark Art Institute in the Berkshires, one of the most remarkable exhibitions I’ve seen in years punches right at the heart of today’s altercations over nationality and democracy, culture and politics, and what it means to be a citizen. Guillaume Lethière (1760—1832) was a Neoclassical painter of mixed race who has never, until now, been the subject of a solo museum show. Born in the French Caribbean, almost certainly into slavery, he reached the summits of artistic achievement in Paris and Rome. As rebellions and revolutions shook both France and the Caribbean, he painted massive history paintings of heroes in togas, and portraits of men and women from Europe and the Antilles. It was Lethière’s calling, in an era where no bonds seemed stable, to give form to fraternité.'
https://www.nytimes.com/2024/07/11/arts/design/guillaume-lethiere-clark-louvre-painter.html
Thiago Carvalho
boosted
Wilson Didn't Resign. The World Suffered. Biden Need Not Repeat That Mistake
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
