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'A situação em Gaza é inimaginável e a inação da União Europeia compromete a sua credibilidade como agente de paz. Para construir a paz na Europa, a União Europeia precisa de um discurso sério e coerente sobre a paz, para ser levada a sério pelo mundo.'

tsf.pt/61549809/catarina-marti

Help! We're Visiting the Small Town Where My Husband Used to Be a Doctor. Everyone Still Thinks We're the Enemy.

slate.com/advice/2024/07/rural

Esquire Entertainment have posted their '75 Best Sci-Fi Books of All Time' list.

I gritted my teeth and clicked through to check - and found a genuinely interesting list, not at all the far too commonly recycled 'stale, pale and male' selections. This doesn't mean it ignores the history of the genre though.

We will doubtless disagree with some rankings and spot omissions according to personal preference, but this is well worth a look regardless.

esquire.com/entertainment/book

#books #SFF #writing

'In this article, we discuss the potential role of N-of-1 trials in cancer drug development in the era of personalized cancer medicine. We also elaborate on a suggested modified design for N-of-1 trials able to overcome limitations and make this concept more applicable to clinical oncology.'

aacrjournals.org/cancerdiscove

SARS-CoV-2 variants for Canada 

"DeFLuQE" sub-variant KP.3.1.1 is tipped as the next significant mutation, with a Spike S31del mutation on top of the successful "FLuQE" platform. It has been most successful in Ontaria.
🧵

'We pair this with a discussion about who has the power to make these changes, from funders to administrators to teachers and people outside of academia. The aim is to teach students that there are people behind the decisions and priorities of academia and research, and thus these issues can be addressed by getting the right people involved.'

onlinelibrary.wiley.com/doi/10

SAVE THE DATES! From 9th-11th August we will be taking over the Crab Museum in Margate. This pincer movement of a colloaboration is set to be clawesome. 🦀

I've been made redundant from my job, effective tomorrow.

So... if you know anyone who's in need of a bioinformatician to work remotely on small bioinformatics projects, please let me know.

Even if you choose to be in denial about the large continuing burden of COVID deaths and Long COVID, allowing the majority of the population get sick with COVID twice a year has a hugely detrimental impact on society. We need long-term and sustainable COVID protections.

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'This is obvious gaming of the system, in order to benefit people who are being evaluated by systems that are themselves set up like some sort of game. It reminds me of the old Soviet joke, "As long as they pretend to pay me, I'll pretend to work". But surely there are better ways to spend ones time and effort - and surely the scientific literature is not served by having yet more garbage dumped into it. I know, this is all happening down in the Lower Depths of the mass of published papers, but floods of sewage need to be addressed in general even if they're not washing over your driveway.'

science.org/content/blog-post/

Longitudinal Multi-Tensor Analysis of Neocortical Microstructure in an Animal Model of Cortical Dysplasia biorxiv.org/content/10.1101/20

'At his rehabilitation medicine practice in Illinois, Dr. Azlan Tariq typically spent seven hours a week fighting with insurance companies reluctant to pay for his patients’ treatments.

He often lost.'

nytimes.com/2024/07/10/health/

'The activation of the STING–MAPK–CREB signaling pathway induces the expression of many cytokine genes, including interleukin-2 (IL-2) and transforming growth factor-beta 2 (TGF-β2), to promote the Treg differentiation.'

pnas.org/doi/10.1073/pnas.2320

'Pfizer is planning to test a daily weight-loss pill in mid-stage trials later this year, as the struggling pharmaceutical group pins its hope on the experimental drug as its route into a market projected to be worth more than $130bn a year.'

ft.com/content/865f8432-6c88-4

'Studies suggest that the virus is spreading between cows through contaminated milking equipment, rather than airborne particles. The biggest risk is that it could evolve to infect mammals more effectively, including through the respiratory system, which would make it more difficult to contain. Given the close and regular contact that cows have with people, airborne transmission could spark a pandemic'
nature.com/articles/d41586-024

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