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"But some tragedies really are catastrophically destructive. The fire at the National Museum of Brazil in 2018 destroyed mountains of unique recordings of indigenous languages, irreplaceable archives of extinct languages, and physical artefacts. When a copy of a book gets burned, it can always be replaced if people care. But much of what was lost that day was lost for good. The fire of Rio de Janeiro was far more destructive than the incidents at Baghdad or Alexandria."

kiwihellenist.blogspot.com/202

A VICTORIAN MERMAN.

Objects like this were sometimes made from the torsos of monkeys and the tails of fish. They were displayed by showmen like P. T Barnum to audiences who believed they were real. This particular one is on display at the Horniman Museum. It was recently x-rayed and curators discovered it had a wooden and wire frame inside with fish skin stretched over its tail. It has rows of teeth that were carved from bone and the hair is human.

Follow me for more #WeirdHistory! #histodon

Why shouldn’t you just delete your #twitter ? Abandoned social media accounts represent the same risk as abandoned domain names. Name #squatting works because reputation and influence gets attached over an account’s life -Those followers you spent time building up don’t just dissipate when you go. For a threat actor this is a huge opportunity. Some accounts carry more #influence than presidents. So if you stop using an account purge it, leave a last message, then securely lock it. (Please share)

RT @yoavrec
🔥 My PhD work is finally published! @CellReports
We showed how running improves neuronal code quality and affects its stability in mice. Here’s a short thread on what we found (and how we studied it) >>
cell.com/cell-reports/fulltext

RT @emollick@twitter.com

Humans are pattern-finding machines & some patterns call to us more.

This neat paper finds that, across 27 cultures, we tend to name the same patterns of stars, mostly because the perceptual systems of humans are all drawn to the same types of patterns. charleskemp.com/papers/kemphlc

🐦🔗: twitter.com/emollick/status/15

RT @BIRDlab_ENS@twitter.com

Louis Pasteur fête ses 200 ans!

Regard, dans @lemonde_science@twitter.com, sur ce personnage scientifique dont les idées en germes ont ensemencé bien des recherches ultérieures et des changements dans la société.

Mais aussi...⏬
lemonde.fr/sciences/article/20

🐦🔗: twitter.com/BIRDlab_ENS/status

'The discussion swirling around immunity debt shows how easy it is for a plausible-sounding theory to circulate as misinformation. In this case, misinformation risks promoting the unfounded assertion that infections are clinically beneficial to children, as well as feeding the revisionist narrative that Covid measures did more harm than good.'

cc @BLMG

ft.com/content/0640004d-cc15-4

RT @SethCheetham@twitter.com

🚨 I am recruiting for a postdoc to develop next-gen mRNA-based therapies. The three-year position will join my passionate team of #mRNA scientists @AIBNatUQ@twitter.com and collaborate with the @BaseDna@twitter.com mRNA facility. DM or email if interested. Please retweet!

uq.wd3.myworkdayjobs.com/en-US

🐦🔗: twitter.com/SethCheetham/statu

'Pancreatic ductal adenocarcinoma (PDA) remains one of the deadliest major cancers, contrasting a relatively low incidence rate1. The primary reasons for this are related to the difficulty with early detection and a lack of effective therapeutic options. A principal barrier to treatment of pancreatic cancer is the densely fibrotic tumor microenvironment, the high interstitial pressure of which acts to collapse blood vessels and impair the delivery of chemotherapy. This lack of functional vasculature leads to deregulated nutrient availability within the tumor, causing cancer cells to develop numerous metabolic adaptations to allow for proliferation under hypoxic and austere conditions'

nature.com/articles/s43018-022

4 yr PhD in Manchester, UK: The evolution of nerves: understanding the roots of neurodegeneration

TRAINING in evol. biol., biochem., expansion or electron microsc., cell culture, #Drosophila genetics, #scicomm

SUPERVISION: Prokop/Allan/Ronshaugen

DETAILS: thenode.biologists.com/jobs/pr

Interesting to see that Editas has paused their #CRISPR clinical trial on Leber congenital amaurosis. More a strategic decision rather than safety concerns over CRISPR therapy.

#CRISPR
#genetherapy

genengnews.com/topics/genome-e

Here's a terrific new paper from one of my classmates about #ImmuneCheckpointInhibitor induced #myocarditis. This work finds that CD8+ T-cells are the critical mediator of heart inflammation, and identifies the alpha-myosin cardiac protein as a candidate autoantigen: nature.com/articles/s41586-022 #science #medicine #immunology #cardiology #oncology #Tcell #genomics #scRNAseq

While carbonidiots of PS & PSD fervently debate new airport locations, I can't get to Madrid by train from Lisbon.

Let's hope this is for real

"Todo ello ocurre, sin embargo, en un momento en el que las líneas ferroviarias entre Madrid y Lisboa siguen atascadas: no existe un tren directo desde que se suspendió hace tres años, algo que solo había ocurrido durante la guerra."

elpais.com/opinion/2022-11-23/

40 years of Love & Rockets

"There were Chicana punk rockers and Southern California skinheads; entire panels of untranslated Spanish; horn-headed gajillionaires and female ex-gang members; and a dialogue-free, noirish fever dream about writer’s block. There were dozens of characters who looked a lot like the people the brothers grew up around, eating, sleeping, laughing, partying, and grousing about work. Much of “Rockets” was set in Huerta, nicknamed Hoppers, a majority Latino town not unlike Oxnard."

nytimes.com/2022/11/19/books/l

Our pre-print "A human-specific motif facilitates CARD8 inflammasome activation after HIV-1 infection" highlighted by the #FredHutch Science Spotlight team fredhutch.org/en/news/spotligh

Work lead by MCBSeattle graduate student @Jkulsuptrakul co-mentored with @psmitchej

Groundhog Day UK

"Six and a half years after voting to leave the European Union, three years after the formal departure, two years after signing a post-Brexit trade deal with Brussels and one month after installing its fourth prime minister since the 2016 referendum, Britain is caught in — what else? — another debate over Brexit."

nytimes.com/2022/11/22/world/e

Excellent new paper from Kyle David finding evidence for a latitudinal gradient of polyploidy in animals. This is similar to what has been observed in plants for many years! Really wonderful! Also good to see our recently published Animal Chromosome Count Database used for the analyses!

#Polyploidy #Animals #Chromosomes #LatitudinalGradient

pnas.org/doi/10.1073/pnas.2214

onlinelibrary.wiley.com/doi/ab

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