Thiago Carvalho @cyrilpedia@qoto.org

'It’s this kind of libertarianism—the you-do-you ethos of American culture that sees the “public” in public health as anathema, clinging to a medical model of private risk and private cures—that dropped us down to the 40s in global life expectancy rankings before the pandemic, and will land us below the 60s by 2040. “Give me liberty and give me death” is the reigning mantra of America today.'
@gregggonsalves

#PublicHealth

https://www.thenation.com/article/society/public-health-covid-pandemic/

"Logbooks, like the nearly 200-page document kept aboard the Eunice H. Adams, served as legal reports, necessary for insurance claims, which meant log keepers kept exhaustive records of the crew’s day-to-day exploits. They tracked the ship’s location, other vessels encountered, and both weather and sea conditions along the routes they sailed. But they also kept clues for the future: Stored within the pages of the 18th and 19th-century whaling logbooks is a cache of ancient weather records, meticulously logged by crews traversing the world’s oceans. "

https://grist.org/article/how-centuries-old-whaling-logs-are-filling-gaps-in-our-climate-knowledge/?ref=the-browser

'The flexible and reversible nature of their reproductive strategies makes facultatively social insects ideal models for understanding the emergence of the simplest forms of reproductive caste (Kronauer & Libbrecht 2018; Shell & Rehan 2018). For example, facultatively social bee taxa have been used to provide evidence for ‘molecular ground plan’ hypotheses (Kapheim et al. 2012, 2020), and to test the long-standing sociogenomic prediction that queen-biased genes should be relatively ancient and conserved compared to worker-biased genes (Jones et al. 2017).'

#Preprint

https://www.biorxiv.org/content/10.1101/2022.12.02.518827v1?med=mas

My latest column for #NatureMedicine is a look at early human results of a new class of #antibiotics for #tuberculosis

The mechanism of action is essentially to clog the #mycobacterium's tRNA synthetase - the result of two decades of research on boron-based compounds.

#IDMastodon #DrugDevelopment
#antibioticresistance

https://www.nature.com/articles/d41591-022-00114-z

'Fifteen scientific journals published a total of 812 (68.7%) of all 1182 papers retracted for being paper mill papers, and 166 (14.0%) were published in one journal, the European Review for Medicaland Pharmacological Sciences. Of these, all journals appear to be non-predatory journals.'

#ScientificPublication #PaperMills #ResearchIntegrity #PeerReview

https://www.bmj.com/content/379/bmj-2022-071517

It seems the Times has found your timeline, @christlet

"Gritty Marseille, France, Is Now a Haven for Creatives"

https://www.nytimes.com/2022/12/02/t-magazine/wanderlust-marseille-france.html

The S in Stanford's original SAB did not stand for "Scientific":

'Among her advantages in their increasingly frosty relationship was her continued communication with her dead husband and son – ‘my two spiritual advisers’, as she called them – whose deceased status rendered them infallible. Under their guidance she laid out a pedagogic vision requiring Stanford students to be taught that ‘every one born on earth has a soul germ’

https://www.lrb.co.uk/the-paper/v44/n23/james-lasdun/stop-all-the-cocks

'A pulse/chase experiment comparing chronically infected to treated animals showed that recently divided Ifng+ T cells, particularly IFN-γ+TNF+IL-2− T cells, are promoted by persistent infection. These data suggest that low-level persistent infection reduces CD4+ Tmem survival and multi-functional Teff but promotes IFN-γ+TNF+IL-2− Late Effector Memory and Terminally Differentiated Effector T cells and prolongs immunity.'

#Immunology #preprint

https://www.biorxiv.org/content/10.1101/2022.12.01.518804v1?med=mas