Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
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Why is a short loop in the extended #Ndc80 #kinetochore complex essential for #mitosis?
In vitro studies by Soumitra Polley @andreamusacchio @microtubule_guy @pim et al reveal its contribution to end-on #microtubule attachment via homotypic interactions between adjacent Ndc80 molecules
https://www.embopress.org/doi/10.15252/embj.2022112504
Thiago Carvalho
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Brazil could face losses of $317 billion per year as well as biodiversity depletion and severe social setbacks for millions of people if Amazon deforestation continues, a new report from the World Bank warns.
The value is seven times higher than profits from commodities taken from the rainforest, the report concludes.
By Sarah Brown
https://news.mongabay.com/2023/05/world-bank-brazil-faces-317-billion-in-annual-losses-to-amazon-deforestation/
Thiago Carvalho
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"The real risk here is that the LLM produced a review report that looks properly balanced but has no specific critical content about the manuscript or the described study. Because it summarises the paper and methodology remarkably well, it could easily be mistaken for an actual review report by those that have not fully read the manuscript."
- Tjibbe Donker in Lancet Infectious Diseases
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00290-6/fulltext
#ChatGPT #PeerReview #AIethics #LLMs #ChatBots #PublicationEthics
Thiago Carvalho
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“Das Rad” (Rocks) is a dystopian short animation film #scifi that posits there won’t be anyone around eventually, and to the slow processes that have always existed will continue as they ever have. Makes the point rather markedly that accelerating growth spells its own demise.
https://m.youtube.com/watch?v=HOPwXNFU7oU&pp=ygURZGFzIHJhZCB0aGUgd2hlZWw%3D
'In the uncensored version, released many decades later, we see that what has been blocked is a jaunty rounded cap. It’s called a kepi, and any French civilian would have recognized it as part of the uniform of the French police. The officer is guarding prisoners at Pithiviers, a transit camp 50 miles outside of Paris where Jewish deportees were put on trains for concentration camps farther east. He’s not a Nazi guard or member of the SS, but there he is, aiding and abetting the Reich.'
https://www.theatlantic.com/books/archive/2023/05/fatherland-book-nazi-germany-review/674129/
Thiago Carvalho
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NAACP issues travel advisory for Florida over DeSantis’ ‘aggressive attempts to erase Black history’
https://www.nbcnews.com/politics/politics-news/naacp-warns-people-color-traveling-florida-rcna85478
Thiago Carvalho
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Thiago Carvalho
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On this day in 1997: Alfred D Hershey died, won 1969 #NobelPrize for working out replication mechanism & genetic structure of viruses #ThisDayInBiotech
'So you want to be a writer...'
A good list by Helen Pearson - in Kaaren Janssen & Richard Sever's collection of essays on "Career Options for Biomedical Scientists" (CSH Press).
Amen to #3.
'But organoids are not ready to represent complex neural networks, says Maria Leptin, the biologist who leads the European Research Council. “You cannot study the function of the brain and its interconnections, even though you can grow brain organoids,” she says. “It will be a long time before questions that require organ interactions or perception can be studied in this way.”
https://www.ft.com/content/7c35e08a-4931-4401-b27e-acabf974bff8?shareType=nongift
'Disease has long been weaponized against those who are perceived as “other.” From the bubonic plague of the 14th century to tuberculosis and H.I.V., the examples echo throughout the history of medicine. When people are frightened, they seek someone to blame, to create a narrative — even if that narrative is false — in which disease is punishment rather than a random unlucky event.'
https://www.nytimes.com/2023/05/21/opinion/the-next-pandemic-blame.html
Thiago Carvalho
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What fine-tunes #mammalian brain connectivity during #development?
Urtė Neniškytė, Cornelius Gross et al identify #Xkr8 #phospholipid #scramblase as responsible for #phosphatidylserine eat-me signal exposure and #axon pruning to prevent global hyperconnectivity
https://www.embopress.org/doi/10.15252/embj.2022111790
Thiago Carvalho
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A new way to measure how a bone fracture impacts life expectancy could help communicate risks to patients with osteoporosis. https://elifesciences.org/digests/83888/how-old-is-your-skeleton?utm_source=mastodon&utm_medium=social&utm_campaign=organic
'As obras ecoam pelas ruas e começam a surgir prédios com nova cara, tal como acontecerá ao edifício onde está instalada a loja de souvenirs de Kazol, que vai passar a hotel. Um pouco acima, uma imobiliária pede 2 mil euros mensais de renda por 50 metros quadrados.'
Thiago Carvalho
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Postdoctoral Position in Molecular Biology and Genetics of Bacteria
Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo - FMRP-USP
FAPESP Postdoc fellowship to research metal homeostasis in bacteria. Join the lab of Prof. José Freire da Silva Neto, FMRP-USP, Ribeirão Preto, Brazil
Thiago Carvalho
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OLD THREAD REPOST
Who wants to hear about some DRAMA? Specifically, huge petty squabbles between 16th century anatomists about clitorises which was also steeped in professional beef and rivalry?
'Gullotta et al. explore ischemic stroke in aged mice and elderly people, identifying age-related alterations in stroke-induced granulopoiesis and characterizing a pathogenic signature of circulating neutrophils that is linked to poorer outcomes. Reversing the neutrophil phenotype in old mice by transfer of young hematopoietic cells improved tissue repair and regeneration after stroke'
Thiago Carvalho
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Works in progress @hunchbacksociety
#ceramics #stoneware #artgallery #handmade #ceramic #artmastodon
Thiago Carvalho
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'Companies have strong incentives to resist studies that could suggest they are responsible for harms involving their products. That’s why future studies will depend on innovations in adversarial data access, ethics and privacy. Researchers should prioritize methods that don’t rely on companies, while supporting laws to require algorithm makers to collaborate with researchers.'
Thiago Carvalho
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Honey Bee Social Immunity
by Roberto
Flying insects are key to the functioning of many ecosystems, where they play numerous important roles such as pollination. Thus, the sharp decline in their numbers is cause for great concern. From a human perspective, the observed demise of many honey bee (Apis mellifera) populations is particularly troubling because of their critical role in the food chain.
Read more → https://schaechter.asmblog.org/schaechter/2023/05/honey-bee-social-immunity.html
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
