Thiago Carvalho @cyrilpedia@qoto.org

#SARSCoV2 ‘overlapping genes’ are often ignored, partly because they are difficult to annotate.

For example, ‘genes’ overlapping ORF3a (3b, 3c, 3d) and N (9b, 9c) may be of great importance—but are not annotated in the NCBI reference genome, Wuhan-Hu-1. elifesciences.org/articles/59633

Not “Everyone” Has Been Infected with COVID https://mikethemadbiologist.com/2023/06/06/not-everyone-has-been-infected-with-covid/

Ion Mobility Mass Spectrometry Unveils Global Protein Conformations in Response to Conditions that Promote and Reverse Liquid–Liquid Phase Separation | https://pubs.acs.org/doi/10.1021/jacs.3c00756 #proteomics

A fiber-free (FF) #MaternalDiet alters #microbiome establishment in pups, with diminished pre-weaning levels of Akkermansia muciniphila (AM). These results underscore the important influence of #MaternalDiet and #microbiome on immune maturation in offspring during a critical developmental period.

By E. Grant, M. Desai & colleagues

👉 https://doi.org/10.15252/emmm.202217241

"Academia’s postdoc system is teetering, imperiling efforts to diversify life sciences"

It takes researchers who do postdocs "about 15 years to catch up in salary to those who hadn’t, and that they earned between $128,000 and $240,000 less in total pay during this period."

via https://www.statnews.com/2023/06/06/postdoc-system-teetering-imperiling-life-sciences-diversity/

h/t @dmacphee

#PostDoc #Science #AcademicChatter

A falta de informação é o novo "não me recordo." É a desculpa para continuar a carregar sobre os salários quando a própria análise do BCE mostra que os lucros são o que tem aumentado verdadeiramente.
RT @IsabellaMWeber: BREAKING: Sellers' inflation is now a Christine Lagarde take.
https://t.co/UQ5rzSmU1U

🐦🔗: https://n.respublicae.eu/joseggusmao/status/1666069275541647360

Hepatic necroptosis and #HCC were caused by recombinant #AAV injection in hyperglycemic and obese mice, which could be alleviated by #prednisone administration or Pebp1/Tbk1 signaling inhibition.

By Y. Cheng, Z. Zhang, Q. Zhai & colleagues at University of Chinese Academy of Sciences

🗞️ https://doi.org/10.15252/emmm.202217230

Gene therapy with AAV vectored micro-dystrophin for Duchenne muscular dystrophy. My latest #ClinicalPipeline column for #NatureMedicine.

#drugdevelopment #SciComm #MuscularDystrophy #Pharma

https://www.nature.com/articles/d41591-023-00052-4

I just love Albrecht Dürer to pieces. You can practically hear the wind blowing over the grasses.

"The Great Piece of Turf"
Watercolor, pen and ink
1503

New article! Read Mapping human norovirus antigens during infection reveals the breadth of the humoral immune response https://www.nature.com/articles/s41541-023-00683-1?utm_source=dlvr.it&utm_medium=mastodon in npj Vaccines

"Dunning-Krugerand" is the best imaginable name for Bitcoin.

'It is instructive to recall (as Davis notes) the legendary six-word short story—“For sale. Baby shoes. Never worn.”—attributed by the literary agent Peter Miller to Ernest Hemingway. Miller claimed that Hemingway won a bet from his fellow writers on the strength of the tale. Arthur C. Clarke wrote to a friend that he could not “think of it without crying.”
(via The Browser)

https://hedgehogreview.com/web-features/thr/posts/the-art-of-compression?ref=thebrowser.com

'There are 14 oncology medicines listed “in shortage” by US regulators, including the generic chemotherapy drugs cisplatin and carboplatin, which are first-line treatments for many common types of cancer.'

https://www.ft.com/content/9225ccd6-df7f-4221-99eb-7ff7142e89f1

'A parte mais relevante é que Moreira Rato defendeu a interrupção da emissão de Certificados de Aforro. Lá se foram os cuidados com a classe média. Claro que Moreira Rato não representa os interesses da classe média e ainda menos o interesse público, como tentou argumentar. A voz de Moreira Rato representa a banca. É chairman do Banco CTT, foi administrador do BES e passou pelo Lehman Brothers.'

https://www.publico.pt/2023/06/05/opiniao/opiniao/joao-moreira-rato-especie-influencer-2052193

The Lisbon rental market is completely out of control - students and postdocs considering moving here should take a page from those going to places like New York and asking about institutional housing.

'Mais ainda quando, no início de Abril, a residência enviou um email a avisar de que a renovação de contratos para o próximo ano lectivo estaria disponível e se confrontou com um aumento de mais de 100 euros. “Fui eu que tive de ir ao site e perceber que tinham aumentado de 695 para mais de 800 euros”, diz Francisco.'

https://www.publico.pt/interactivos/habitacao-estudantes-lisboa-residencias-universitarias/