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'High cholesterol in the over-40s and hearing impairments were most commonly associated with people developing dementia globally, according to new research by The Lancet Commission on dementia prevention, intervention and care.'

ft.com/content/20422086-56cb-4

'Analyses of R&D spending and equity investment in biotech predict that the industry is capable of weathering a drop in revenue due to lower drug prices, with no corresponding loss in new approved drugs.'

fiercebiotech.com/research/ana

'Health problems and brain fog can persist for years in people hospitalised by Covid early in the pandemic, with some patients developing more severe and even new symptoms after 12 months, researchers say.'

theguardian.com/world/article/

#IDMastodon #Immunology #Immunology #Bcellbiology Overview roles of #autophagy on #Bcell development, maturation & Their capacity to generate long-lasting #humoralimmunity immunity against microbial pathogens enables #Bcells to protect the host against repeated infections, which provides the mechanistic basis for vaccine efficacy

frontiersin.org/journals/immun

REVEALED: The Russian-linked fake news website which fuelled lies about the Southport stabbings and sparked violent protests | Daily Mail Online

dailymail.co.uk/news/article-1

Well, it's the Daily Mail, but there you have it. A link to the only foreign actor that could really profit from instability in the UK...

#fascism #putin #kremlin #southport #uk

'In 2011, a Dutch woman named Ellen Novara-da Lima sent Sacks an e-mail. “I am a woman of 52 years old and I suffer from an illness,” she wrote. “I think there’s no name for it. I see monsters, ugly faces all day.”'

Fascinating new research on a mysterious and rare neurological condition being carried out at Dartmouth College

newyorker.com/news/annals-of-i

“Study Finds Consumers Are Actively Turned Off by Products That Use AI”

futurism.com/the-byte/study-co

> When AI is mentioned, it tends to lower emotional trust, which in turn decreases purchase intentions

Like I've been saying, we don't need the term "slop". Consumers have decided that "AI" in its entirety is bullshit. And, honestly, they’re right.

One of the most ominous risks for Europe is that of a major change in Atlantic ocean currents.
Recent science suggests it has been greatly underestimated in the past -including by me, having worked on it for over 30 years.
My half-hour presentation explains the key facts you need to know!

youtu.be/ZHNNW8c_FaA?si=3eqXk3

'We used Bacillus Calmette-Guerin (BCG), a live-attenuated vaccine, to train the innate immune system and detected epigenetic reprogramming of brain-resident myeloid cells and functional restoration of myelin debris clearance and lesion recovery.'

cell.com/immunity/fulltext/S10

Study shows long term cardiovascular complications of Covid, including mld acute infections, in college students.

#COVID #LongCovid bmcinfectdis.biomedcentral.com

‘They broke our hands and feet’: Israel releases 15 Palestinian prisoners youtube.com/watch?v=6BOJtXLSn3

'The government should look at ways of making it easier for medics to adopt new life-saving innovations. A framework for sepsis and infection management, akin to those for heart attack and stroke, would also help. As Daniels notes, sepsis affects more people than heart attacks and claims more lives than strokes.'
ft.com/content/9537418a-8796-4

Genomes fm chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan, and siamang:
"We resolve challenging regions, such as the major histocompatibility complex and immunoglobulin loci, providing more in-depth evolutionary insights."

biorxiv.org/content/10.1101/20

Why don't you actually like coriander?

It's chromosome 11.

Variations in the OR6A2 gene have been identified as the likely cause of why some people like the smell and taste of coriander, while others have the exact opposite reaction.

Depending on its origin, somewhere between 3% and 21% of the population associate it with an unpleasant taste, including a combination of soap and vomit, or say that it is similar to the foul odor emitted by stink bugs.

#coriander #dna #Science

'What's surprising is that these things don't go on to show the same toxicity to eukaryotic cells, and I have to say, I wouldn't have expected that, especially since the initial screens used eukaryotic DNA). But the degree of DNA-induced aggregation correlates quite well with the antibacterial activity (and for that matter, the degree of self-aggregation is a pretty good surrogate for the DNA-induced aggregation).'
science.org/content/blog-post/

'Cheap and efficient assessment methods that can be used in distance education, such as unsupervised online tests, spread with the Covid-19 pandemic. Yet, with the pandemic now behind us, many such assessments that are vulnerable to cheating are still used more than they used to be by time-poor academics in cash-strapped universities.'
theguardian.com/australia-news

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