Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
'Segundo a organização de defesa de direitos humanos Avós da Praça de Maio, cerca de 500 bebés foram roubados pela ditadura aos pais, na sua maioria opositores ao regime, e, em muitos casos, a mães que deram à luz em centros clandestinos de detenção e tortura e que desapareceram para sempre, foram assassinadas ou atiradas com vida, mas drogadas, para o mar.'
Thiago Carvalho
boosted
Research Priorities of Individuals and Families with Sex Chromosome Aneuploidies https://www.medrxiv.org/content/10.1101/2024.08.15.24312069
'Biologists in local offices contributed to decisions about things like how many deer could be hunted each year, or how to protect rare salamanders. “But few were looking at disease, really,” she said. “The thinking was that it was natural for a disease to run through wildlife and therefore it was not a concern.”
https://www.newyorker.com/science/elements/the-veterinarians-preventing-the-next-pandemic
Thiago Carvalho
boosted
Exposures and conditions prior to age 16 are associated with dementia status among adults in the United States Health and Retirement Study https://www.medrxiv.org/content/10.1101/2024.08.15.24312018
'Although the distant view takes up far less space in the composition than the interior scene, no other element holds the eye for so long. It feels as though if you could only get closer you would see still more. The art historian Erwin Panofsky called the Rolin Madonna, for good reason, “the ne plus ultra in landscape painting.”
Thiago Carvalho
boosted
Lawsuits are expensive.
The Republicans funding these lawsuits needs to be public knowledge.
https://www.rollingstone.com/politics/politics-news/trumps-financial-disclosures-liabilities-grifts-crypto-1235081631/
https://www.newsweek.com/donald-trump-owes-millions-lawsuits-financial-disclosures-show-1940139
https://nymag.com/intelligencer/article/what-are-the-legal-cases-against-donald-trump.html
https://slate.com/news-and-politics/2023/05/has-anyone-been-sued-more-than-trump.html
Thiago Carvalho
boosted
Twitter migration
I just ventured onto TwiX. Saw some scientists saying that they had had enough and were quitting. One reply said “we need an ethical alternative platform”.
I am totally mystified. The fediverse is right here!
#PreachingToTheChoir #HorseToWater
Thiago Carvalho
boosted
A Very Good Sign: Kamala Harris Is Going Right at Corporate Greed
Immediately before the pandemic, corporate profits were 9.7 percent of the total GDP.
👉From 2020 to 2023, they spiked to an average 11.2 percent of annual GDP.
⚠️The disparity between those two numbers amounts to a jaw-dropping $1.5 trillion more of our economy that was transferred over to corporate profits in the last four years.
😨That money was picked directly from the pockets of American families,
who each paid $12,000 more to plump the profit margins of corporations
(and that’s not even counting the excess APR rates that have cost the average credit card user $946 over the same four-year period).
This is unsustainable.
⭐️By taking a stand against those CEOs and bringing prices back down for the American people,
🔥Harris can ensure that the American people continue to make our economy the envy of the world.
A healthy economy is an ecosystem where companies compete for consumers
—and also for workers, which leads to lower prices and higher wages.
Those higher wages result in stronger consumer demand, which causes businesses to create more jobs.
✅Everyone benefits from this virtuous cycle of inclusion, innovation and demand.
❌And everyone loses when a greedy few CEOs addicted to soaring profits are milking us dry.
https://newrepublic.com/article/184937/harris-price-gouging-corporations
Thiago Carvalho
boosted
'These age-associated TECs (aaTECs) formed high-density peri-medullary epithelial clusters that were devoid of thymocytes; an accretion of nonproductive thymic tissue that worsened with age, exhibited features of epithelial-to-mesenchymal transition and was associated with downregulation of FOXN1'
#Immunology
https://www.nature.com/articles/s41590-024-01915-9#Sec2
Thiago Carvalho
boosted
'Com o aumento da esperança de vida e um desenvolvimento científico que cria novas expectativas, a pressão sobre o SNS é muito maior e a saúde custa, no público ou no privado, muito mais. Ou desistimos de garantir a todos o melhor do progresso em saúde ou desistimos do alívio geral de impostos, optando por distribuir melhor encargos fiscais crescentes.'
https://expresso.pt/opiniao/2024-08-14-pactos-e-batatinhas-e3331880
'We have investigated cold RNA biochemistry using single-RNA force spectroscopy. At low temperatures, we find that sequence-independent contributions of RNA–water interactions outweigh sequence-dependent base pairing, leading to misfolding of fully complementary hairpins.'
Thiago Carvalho
boosted
How MIT copes without Elsevier
MIT leaders describe their experience of not renewing the largest journal contract as "overwhelmingly positive". Read what happened after they cancelled...
http://druedin.com/2024/08/16/how-mit-copes-without-elsevier/
Thiago Carvalho
boosted
Profound and beautuful and wow:
ALS (which afflicted Stephen Hawking and Lou Gehrig) is a terrible neurodegenerative disorder. Researchers have been working to create brain-computer-interfaces to restore communication when patients become locked-in (conscious but unable to communicate) with notable sucess (like they imagine writing letters and they appear on a computer screen). But it’s all a bit tedious and finiky.
One researcher, now an Assistant Professor at UC Davis (Sergey Stavisky) had an idea: if we read out signals from the bits of the brain not used for motor functions like writing but the ones used to speak … well … just watch the video. CW: tears might be shed.
'A Direção-Geral da Saúde (DGS) esclareceu esta sexta-feira que nenhum dos casos de monkeypox (mpox) reportados em Portugal é da variante mais perigosa da doença (clade I), que apareceu na quinta-feira pela primeira vez na Suécia.'
Thiago Carvalho
boosted
"Apart from being deranged, Donald Trump is an idiot."
-- Charlie Sykes
'Ruthenium is abundant in asteroids but extremely scarce in Earth’s crust, making it a handy bellwether of past impacts by space rocks. The team searched for isotopes of ruthenium in the geological remnants of the Chicxulub impact.'
https://www.nytimes.com/2024/08/15/science/asteroid-dinosaurs-chicxulub.html
'However, the evolutionary comparisons of sex-biased gene expression have so far focused on comparisons between relatively distant species and relatively few individuals per species only (Naqvi et al., 2019; Rodríguez-Montes et al., 2023), making it difficult to gauge the true evolutionary rates. Here we use the house mouse radiation to address the evolution of sex-biased genes and their expression.'
https://elifesciences.org/reviewed-preprints/99602
Thiago Carvalho
boosted
As 2024 progresses, we’re now several months into a surge of #COVID19.
COVID-19 hasn’t gone away. It’s still making us sick and still disabling people with #LongCOVID. Wearing a mask helps keep you from getting the virus and spreading it to others—the flip side of which is, not masking enables you to get infected and to spread it to others.
For this reason, San Francisco’s Department of Public Health has encouraged residents to wear masks in crowded indoor spaces: https://www.sfchronicle.com/health/article/mask-recommendation-covid-san-francisco-19599948.php
And in just a month or so, we’ll have a new round of COVID-19 vaccines for 2024–2025. Make sure to get yours—and your flu shot—promptly. Vaccines help you get less sick when you do get COVID-19, and make it more likely that you’ll make a full recovery.
COVID-19 is a part of our present reality and will be for the foreseeable future. We can maintain healthy, full lives by acting accordingly.
'I had not been to Israel since June 2023, and during this recent visit I found a different country from the one I had known. Although I have worked abroad for many years, Israel is where I was born and raised. It is the place where my parents lived and are buried; it is where my son has established his own family and most of my oldest and best friends live. Knowing the country from the inside and having followed events even more closely than usual since 7 October, I was not entirely surprised by what I encountered on my return, but it was still profoundly disturbing.'
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
