Thiago Carvalho @cyrilpedia@qoto.org

'Entomologists like Sial enjoy telling people that, left to their own devices for a year, a male fruit fly and a female fruit fly—the latter of which can lay hundreds of eggs during her brief lifetime—could theoretically coat the surface of the planet with their descendants, in a layer dense enough to “fill the space between the Earth and the moon” … twice.'

https://www.theatlantic.com/science/archive/2023/04/get-rid-of-fruit-flies-kitchen-compost-pile-bin/673766/

'Los papeles demostraban que los ejecutivos de la tecnológica eran conscientes de que los algoritmos de Facebook e Instagram difundían entre los adolescentes, especialmente entre las chicas, las bondades de la anorexia o incluso pensamientos suicidas. De acuerdo con una investigación propia de la tecnológica, el 6% de los adolescentes estadounidenses y el 13% de los británicos que decían haber sopesado la idea de suicidarse lo habían hecho impulsados por Instagram.'

https://elpais.com/tecnologia/2023-04-22/las-nuevas-tabaqueras-la-oleada-de-demandas-que-puede-acabar-con-las-redes-sociales.html

'So what now of Sunak, the hardest man in the luxury knitwear aisle? We began the week with the prime minister’s much-vaunted reannouncement about trying to raise standards in maths. We end it with him having reluctantly subtracted one cabinet minister from his table, and under personal investigation for an alleged failure to declare his wife’s shares in a private childcare company that stands to benefit from his government’s plans to get more people to become childminders.'

https://www.theguardian.com/commentisfree/2023/apr/21/dominic-raab-hardman-rishi-sunak-scandal?CMP=share_btn_tw

Thirty two!

Hunting submarines.

'Here, we report that CD8+T cells maintain the capacity to kill tumor cells that are entirely devoid of MHC-I expression. This capacity proves to be dependent on interactions between T cell NKG2D and tumor NKG2D ligands (NKG2DL).'
#Preprint #immunology #immunooncology #immunotherapy

https://www.biorxiv.org/content/10.1101/2023.02.02.526713v1

'In the Ts65Dn mouse model for DS, where DSCAM is overexpressed due to DSCAM triplication, GABAergic innervation of PyNs by basket and chandelier interneurons is increased. Genetic normalization of DSCAM expression rescues the excessive GABAergic innervations and the increased inhibition of PyNs. Conversely, loss of DSCAM impairs GABAergic synapse development and function.'

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002078

'Two affirmative action lawsuits facing the court—against the University of North Carolina (UNC) and Harvard University—will likely have severe ramifications for medical training and health equity. Given the likelihood that the Supreme Court will end affirmative action, medical institutions must plan how to further diversity without incurring liability.'

https://www.pnas.org/doi/10.1073/pnas.2220919120

It was a pleasure to reconnect with José Roberto de Toledo of Brazil's Piauí magazine a couple years after participating in his Portuguese language Pandemic Podcast, "Luz no fim da Quarentena" (ht @mucida).
On UOL's Análise de Notícia we talked about the new #malaria and #RSV #vaccines.
👇 Starts around min 27 (in Portuguese)

https://www.youtube.com/watch?v=N68508vkQ-8

"The biggest mystery is Bogner himself, who entered the influenza field in 2006 without any known links to research or science policy. Science’s investigation has found that Bogner has a checkered and murky past. Official documents list different birth dates. In his early 20s, Bogner was convicted of securities fraud—a previously unreported felony for which he spent time in jail—and had a falling out with a World Cup skier over funding and credit for an instructional video."

https://www.science.org/content/article/invented-persona-behind-key-pandemic-database