Thiago Carvalho @cyrilpedia@qoto.org

'Outside of mammals, few examples of immunostimulatory LPS activities (or LPS receptors) exist. Indeed, the genes encoding the mammalian LPS receptors CD14, TLR4, and MD2 are absent from the genomes of fish and invertebrates (which constitute >90% of metazoan life). Thus, exceptions to the error-centric theme of pattern recognition may be a recent evolutionary innovation'

https://www.science.org/doi/10.1126/science.ade9733

'Health-sector governance should promote collaboration and solidarity between countries, not encourage competition and gatekeeping in the development of lifesaving products. The pandemic has already demonstrated why we need such a shift in perspective.'

https://www.project-syndicate.org/commentary/drug-development-health-innovation-public-funding-needs-more-conditions-by-mariana-mazzucato-2023-04?barrier=accesspaylog

Beatrix Potter is best remembered for her charming tales of Peter Rabbit, but did you know she also studied #science?

Potter collected & examined beetles, butterflies, plants, bird eggs, shells, rocks, fossils & especially fungi. She conducted experiments & wrote a scientific paper with her own illustrations, presented at the Linnean Society of London. However, as a woman in the Victorian era, she couldn’t even attend the meeting. https://www.nytimes.com/2023/04/26/arts/design/beatrix-potter-peter-rabbit-science.html?smid=nytcore-ios-share&referringSource=articleShare #HistoryRemix #history #art #books

Associate Research Scientist @ZuckermanBrain

https://jobrxiv.org/job/associate-research-scientist-11/?feed_id=44172

#ScienceJobs #job
New York City #UnitedStatesUS #Researcher #Scientist
https://jobrxiv.org/job/associate-research-scientist-11/?feed_id=44172

To celebrate May Day, read this paper about how unpaid internships/volunteer work in STEM only amplify inequality….

…and then stop running your labs on volunteer labor ❤️

https://github.com/aurielfournier/aurielfournier.github.io/blob/master/_pdfs/Fournier_et_al_2019_PlosOne.pdf

'More than 75 members of the National Academies of Sciences, Engineering and Medicine demanded on Thursday that the organization explain why it has for years failed to return or repurpose millions of dollars donated by the Sackler family, including some who led Purdue Pharma.'

https://www.nytimes.com/2023/04/28/health/national-academies-sacklers.html?action=click&module=Well&pgtype=Homepage&section=Health

A useful rule of thumb is 'if Thomas Boehm is giving a seminar in your general geographic area, go'.

'The bloc is negotiating an amended deal with Pfizer despite the European public prosecutor opening a criminal investigation into their original agreement'

https://www.ft.com/content/fbcd28ad-f39a-4eae-8ffd-1baf940f41f1

'El Gobierno de extrema derecha de Giorgia Meloni ha planteado sus políticas en materia de migrantes bajo la enseña de la inhumanidad. Empezando por la vergüenza del estado de emergencia, que permitirá a la presidenta del Gobierno italiano emitir órdenes ministeriales sin debatirlas en el Consejo de Ministros y mucho menos en el Parlamento'

https://elpais.com/ideas/2023-04-23/la-crueldad-en-el-vertice-de-europa-meloni-migrantes-y-politica.html

PHOTOS DUE THURSDAY, MAY 4! Enter your finest insect photography for the chance to be featured in the 2024 World of Insects Calendar. Photos may also be considered for "Arthropod Photo of the Week" or on one of ESA's scientific journal covers. Learn more and submit your photos: https://www.entsoc.org/publications/world-insects-calendar

“I think it’s way past time to do full-scale user research and design work on ways to integrate some kinds of search and quotation in some places and in ways that preserve privacy, safety, and autonomy. And to handle the whole nested doll of problems related to sign-up, discovery, and following, for starters.”

Superb piece by @kissane addressing the most worrisome question about Mastodon: How DOES it change for the better? Where does change come from, when it’s needed? https://erinkissane.com/blue-skies-over-mastodon

Beautiful Brain – the stunning drawings of neuroscience founding father Santiago Ramón y Cajal, born on this day in 1852 https://www.themarginalian.org/2017/02/23/beautiful-brain-santiago-ramon-y-cajal/

'Scientists have long known that dense breast tissue is linked to an increased risk of breast cancer in women. A study published on Thursday in JAMA Oncology adds a new twist, finding that while breast density declines with age, a slower rate of decline in one breast often precedes a cancer diagnosis in that breast.'

https://www.nytimes.com/2023/04/28/health/breast-cancer-density.html?action=click&module=Well&pgtype=Homepage&section=Health

'The founders of Melbourne’s Steam Room program believe scientists can make their work more accessible through humour. Will their hypothesis prove true?'

https://www.theguardian.com/science/2023/apr/30/the-science-of-standup-can-you-train-someone-to-be-funny