Thiago Carvalho @cyrilpedia@qoto.org

We shared our streets before cars 🚗 🚙 took over 👇👇

San Francisco 🇺🇸 100 years ago

This week, I highlight the work of Zhu et al. in Nature Immunology. The authors examined the effects of stress on the gut microbiota in mice and found that changes in a Lactobacillus species were associated with increased numbers of IL-17-secreting gamma-delta T cells in the gut. These cells migrated to the meninges and were associated with changes in behavior. Targeting this axis may have therapeutic benefits for patients with depression. Read a summary: https://www.science.org/doi/10.1126/scisignal.adi4514 #neuroimmunology

Associate Research Scientist @ZuckermanBrain

https://jobrxiv.org/job/associate-research-scientist-12/?feed_id=44274

#ScienceJobs #job
New York City #UnitedStatesUS #Researcher #Scientist
https://jobrxiv.org/job/associate-research-scientist-12/?feed_id=44274

Anti-monarchists receive ‘intimidatory’ Home Office letter on new protest laws
#Coronation #ProtestBill #NotMyKing https://www.theguardian.com/politics/2023/may/02/anti-monarchists-receive-intimidatory-home-office-letter-on-new-protest-laws-coronation?CMP=Share_iOSApp_Other

'Recently, a proof-of-concept study demonstrated the idea of “humanizing” zebrafish. Simply, introduced hematopoietic stem cells and human monocytes/macrophages into larval zebrafish retained tissue specific function.'

https://www.cell.com/cell/fulltext/S0092-8674(23)00169-1

'Other Covid vaccine mandates have already been relaxed by colleges, local and state governments, and private companies. But the end of federal vaccine requirements will have an immediate impact on tens of thousands of Americans, as well as foreigners who travel to the United States.'

https://www.nytimes.com/2023/05/01/us/politics/us-covid-vaccine-mandates.html

'Dr. Hinton said he has quit his job at Google, where he has worked for more than a decade and became one of the most respected voices in the field, so he can freely speak out about the risks of A.I. A part of him, he said, now regrets his life’s work.'

https://www.nytimes.com/2023/05/01/technology/ai-google-chatbot-engineer-quits-hinton.html

In our latest interview on preprints and the future of peer review, Marcel LaFlamme (@marcellaflamme) of @PLOS spoke to us about the relationship between Review Commons and our partner journals, how peer review work deserves proper credit and a look to the future of machine-assisted peer review.

https://www.reviewcommons.org/blog/the-multiple-uses-of-peer-review-an-interview-with-marcel-laflamme/

#PeerReview #preprint #publishing

We want to make science and #PeerReview more transparent and open.
Do you want to join us?
It's easy.

When invited by platforms such as @PeerCommunityIn, @ReviewCommons, Rapid Reviews\Infectious Diseases, and @eLife agree to review #preprints

Let's improve peer review together! 💪

#research #ECR #OpenScience #preprints #publishing #PublishYourReviews

In their #JEB100 Review, @GlennaClifton @NickGravish & co discuss how rough surfaces influence animal walking and they propose terminology and a metric for characterizing the relative roughness compared with animal size to enhance comparative studies

#biomechanics #zoology #biology #sciencemastodon

https://journals.biologists.com/jeb/article/226/Suppl_1/jeb245261/307149

An important thing to keep in mind with all the talk about intranasal #Covid vaccines: this type of vaccine is tough to make. If they were easier to make, we'd have more of them.@dr_kkjetelina & @ENirenberg https://yourlocalepidemiologist.substack.com/p/hype-or-hope-nasal-covid-19-vaccines

A long & winding road.

"However, our efforts to identify a chemical inhibitor of apoptosis floundered. Whatever we tested either did not work or had only a marginal effect. We wondered whether components of the pathway might have built-in redundancies. If so, the project was dead."
#Apoptosis #CellDeath

https://www.science.org/doi/10.1126/sciadv.adi2011#.ZEmbzTtPNQI.twitter

The #RandomLaboratory model allows one to estimate whether an experimental result is likely to #replicate. This study uses new experimental data to show that such a model, when applied to archived data, improves prediction of #replicability #PLOSBiology https://plos.io/40YEv5b

“Pay for grad students hasn’t increased in 20 years, while there has been 50% inflation over the same period,” says Sarah Laframboise, a biochemistry PhD student at the University of Ottawa and executive director of Support Our Science, a student-led campaign group that is organizing the walkout.'

https://www.nature.com/articles/d41586-023-01453-8