Thiago Carvalho @cyrilpedia@qoto.org

“She loved to drink, on doctor’s orders of course, and would sit for hours absorbing whiskey-and-soda and Al’s talk. He was wonderful with her; he would start with palmistry, and without her knowing it end with Das Kapital.”

#Books #FoodWriting #Bookshelf #BookClub #Reader #MFKFisher #bookstodon

'We found that the follicular dendritic cell network was smaller in aged mice. Furthermore, the TFH cells that are normally localized within the light zone were instead dispersed throughout the GC in aged mice (Fig. 1), owing to enhanced expression of CXCR4 (a CXCL12 receptor) that directed the TFH cells to the CXCL12-rich dark zone.'
#Immunology #GerminalCenter

https://www.nature.com/articles/s41590-023-01520-2

'The HPV vaccine, which offers near-total protection against the sexually transmitted virus that causes cervical cancer, has been given to adolescents in the United States and other industrialized countries for almost 20 years. But it is only now starting to be widely introduced in lower-income countries, where 90 percent of cervical cancer deaths occur.'

https://www.nytimes.com/2023/05/23/health/hpv-vaccine-tanzania.html?action=click&module=Well&pgtype=Homepage&section=Health

"For now, there is much to enjoy in Braverman’s sense that she was simply too famous and too distracting to do an online speed awareness course with the plebs. In fact, as attorney general at the time, Suella surely enjoyed a greater degree of anonymity than that afforded by even the better witness protection programmes."

https://www.theguardian.com/commentisfree/2023/may/23/westminster-suella-braverman-three-points-speed-awareness-course

Prostate cancer #organoid models.

"In summary, the availability of a tractable culture system for the in vitro growth of a variety of progenitor and differentiated prostate epithelial cells has facilitated the identification and molecular characterization of normal and transformed subpopulations as well as transient changes that occur in these subpopulations (46), deepening our understanding of the mechanisms of transformation underpinning prostate cancer."

https://www.jci.org/articles/view/169616

'Our comprehensive genomic survey revealed that 14 to 40 kbp long DNA viruses of the Polinton-like supergroup are frequent inhabitants of diverse protist genomes. Moreover, our finding of thousands of endogenous viruses in one-third of all sequenced protist genomes may still be a conservative estimate.'

#Virology

https://www.pnas.org/doi/10.1073/pnas.2300465120#sec-2

'Twitter has long been described, even by its most ardent users, as a hellsite. But under Elon Musk, Twitter has evolved into a platform that is indistinguishable from the wastelands of alternative social-media sites such as Truth Social and Parler. It is now a right-wing social network.'

https://www.theatlantic.com/technology/archive/2023/05/elon-musk-ron-desantis-2024-twitter/674149/

The people who brought you this train wreck had another bright idea (in Portuguese):

"A Universidade de Lisboa permanece alicerçada nas duas universidades extintas, com ofertas educativas incoerentes e concorrentes, fracas sinergias no ensino e investigação entre as faculdades, um corpo docente envelhecido e diminuta unidade – potenciadora de movimentos como o que surgiu recentemente no Instituto Superior Técnico (IST), defensor da saída deste da Universidade de Lisboa."

https://www.publico.pt/2023/05/24/ciencia/opiniao/novo-fusao-instituto-gulbenkian-ciencia-instituto-medicina-molecular-2048996

'Icahn alleges that Thompson and deSouza championed a “reckless decision” to close Illumina’s $8bn acquisition of cancer test developer Grail in 2021 against the wishes of EU and US antitrust regulators. Illumina’s market capitalisation has plunged from $75bn in August 2021, when it bought Grail, to just over $32bn on Tuesday.'

https://www.ft.com/content/16021817-6202-4f38-8af9-3932bf555aa8