Thiago Carvalho @cyrilpedia@qoto.org

Bluesky won't be a good fit for everyone, but for the science-inclined that do make their way there, be sure you land in the What's Science feed organized by @bossett.bsky.social

"‘Cybernetics and Ghosts’, the 1967 lecture that begins with the tribal storyteller, took its inspiration from avant-garde experiments with basic computers. Calvino thought that the use of machines to destabilise literary form, or produce generative disorder, was eminently human. The machine’s ‘true vocation would be for classicism’, having the capacity to infer and follow stylistic rules exactingly. It is interesting to revisit this argument in the era of AI, not least in light of Calvino’s brief, teasing claim that a true ‘literature machine’ would produce avant-garde work ‘to free its circuits when they are choked’ by classicism"

https://www.lrb.co.uk/the-paper/v45/n12/james-butler/infinite-artichoke

Madrid

In little more than a decade of feverish work, Robert Frank broke the rules of documentary #photography and reset the template for postwar photogs who plied their art with a camera on the street

Here, a young man is carrying a tulip--maybe for the woman in the background? An older man approaches. It's a classic romantic #Paris street photo. The knowledge that Frank had gotten a friend to pose explains how the #photograph came to be — without diminishing its charm

"Tulip/Paris," 1950 #history

#pancreaticcancer is a deadly disease. New #trial data shows early benefits for addition of a personalized #mRNA #vaccine to #adjuvantchemotherapy after resection of the tumor. This feature in Deutsche Welle discusses the implications with Nina Bhardwaj and Drew Weissman #Immunotherapy #oncology https://t.co/j81AOXjcJS

@cyrilpedia Fully agreed! It is not understandable, why still no standard format for all first submissions exist...a simple json or XML type basic layout would be so easy and each journal could build a simple conversion tool to even produce PDFs automatically...

'A global comparison of the long-read data from young and aged mice showed an age-associated increase in the expression of noncoding transcripts, including IgV pseudogenes, lncRNAs and transcripts with retained introns (Supplementary Fig. 7). This is consistent with observations that an increased frequency of intron retention has been identified as a signature of ageing in fruitfly, mouse and human'

https://www.nature.com/articles/s42003-023-04936-6

AstraZeneca invests in Tregs

"One of the most promising UK biotech start-ups, Quell Therapeutics, has signed a research collaboration and licensing deal with AstraZeneca to develop treatments for two autoimmune diseases."

https://www.ft.com/content/92b0e9d5-22c1-4ddd-b135-52de8e200a48

It's official - we have a business! More news soon.

Celebrating with David del Álamo in Madrid.

This is just a ludicrous policy. Think of it this way: what would happen if Australia, Japan, South Africa or India asked for the lab notebooks of American researchers every three months? This is ill-considered policy, which will dissuade global health research. This is on NIH and HHS. They put this in place. They need to fix it.

https://www.nature.com/articles/d41586-023-01930-0

@halama_immuno @physorg_bot @gpollara Absolutely - but there are some very interesting details here, like this one "For instance, we find that bats have either lost CARD8 or have a CARD8 protein that is antagonized, rather than activated, by coronavirus 3CLpro cleavage."

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002144

June 9, 1891, French painter Paul Gauguin arrives in Papeete, Tahiti - a landscape of Tahiti with #volcano 🌋🖌️