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Hi #ScienceMastodon.

#preLights (prelights.biologists.com) is a #preprint highlights service run by the biological #community & supported by #Co_Biologists allowing one to:

🔎 Sift through the high # of preprints.
💡 Highlight new thinking/techniques across the biological sciences.
📝 Comment on preprints.
👥 See comments & opinions of others.

We’ve moved over to our own instance @biologists.social, & hope that you’ll join us there for friendly chats between biologists!

biologists.social/about

Looks interesting, Heng Li proposes a faster #BUSCO: "miniBUSCO achieves a 14-fold speedup over BUSCO. Furthermore, miniBUSCO reports a more accurate completeness of 99.6% than BUSCO’s completeness of 95.7%, which is in close agreement with the annotation completeness of 99.5% for T2T-CHM13"
biorxiv.org/content/10.1101/20 #bioinformatics #HumanGenome #genomics

At #GRCdevbio23,
@tinalab_inStem (@DBT_inStem) brings together metabolism, growth and the immune system.

Learn more about Tina's work with
@m_goyal08 and colleagues in
@Dev_journal: journals.biologists.com/dev/ar

Harvard professor Francesca Gino, who studies 'Honesty', has been accused of using fraudulent data in her research. Gino has been accused of fabricating data on four different research papers spanning over a decade. nytimes.com/2023/06/24/busines

Hi #ScienceMastodon. @focalplane_jcs is your #microscopy community site hosted by @J_Cell_Sci & @Co_Biologists, connecting people, resources & info.
Anyone can contribute on focalplane.biologists.com. We’ll be tooting the latest news & posts from the #community. You can also join and use the FocalPlane Network to make new connections.

We’ve just moved over to our own instance @biologists.social, & hope that you’ll join us there for friendly chats between biologists!
biologists.social/about

Hungarian Prime Minister Viktor Orban said that Russian President Vladimir Putin, in his opinion, is not a war criminal. Putin puppet Orban needs to be made to heel. NATO needs a suspension and removal mechanism for when states no longer meet requirements.
#StandWithUkraine

Hi #ScienceMastodon. We, @J_Cell_Sci, are a community journal covering all areas of #cellbiology. Journal of Cell Science is led by Editor-in-Chief Michael Way & published by the not-for-profit @Co_Biologists.
We will toot about our content, including #research papers, #reviews, #interviews, charitable activities, and news from @focalplane_jcs.
We’ve moved over to our own instance @biologists.social, & hope that you’ll join us there for friendly chats between biologists!
biologists.social/about

The current structure of science funding would make Max Perutz's work impossible and Perutz unemployed:

"Max, inspired by Bernal's vision that the structure of large and complex molecules such as proteins could be solved using X-ray diffraction, embarked on scaling a mountain in biology—solving the structure of haemoglobin. This was to take him more than 20 years."

embopress.org/doi/full/10.1093

Hi #ScienceMastodon. @the_node is the community website for and by developmental and stem cell biologists, where you can read the latest #devbio and #stemcell biology news, check out jobs and events pages and interact with colleagues from around the world.

The Node is run by the journal @Dev_journal and its publisher, @Co_Biologists.

We’ve moved over to our own instance @biologists.social, & hope that you’ll join us there for friendly chats between biologists!

biologists.social/about

PepFlow: direct conformational sampling from peptide energy landscapes through hypernetwork-conditioned diffusion | biorxiv.org/content/10.1101/20 #proteomics

👨‍🔬👩‍🔬Together we win! Thanks to the collaboration with Università di Torino we'll be pioneering the development of advanced methods for detecting cancer biomarkers using oligonucleotide sequencing.

🔬Our #CollaborActions 👉humantechnopole.it/en/research

#science #sciencemastodon #lifesciences #humantechnopole

'Virus-based vectors — particularly those based on adeno-associated virus (AAV) and lentiviruses — have dominated the first wave of gene therapies to gain regulatory approval. But their widespread deployment in dozens of clinical trials has exposed their limitations.'

nature.com/articles/s41587-023

Cada día que pasa queda más clara la impertinencia de la política oficial de la Iglesia española de que "la ropa sucia se lava en casa" cuando cada día que pasa queda más evidente que la suciedad no está en la ropa, está en la casa elpais.com/sociedad/2023-06-26

"I love that Odysseus and Achilles are complete disasters as heroes; they made terrible mistakes. They’re incredibly proud and angry. They reign destruction down on the people around them—the people that they love, not just their enemies. Achilles’s name—there are a couple different etymologies for it, but likely it comes from grief to the people. Odysseus’s name is related etymologically to the word that means to be hated."

publicbooks.org/madeline-mille

Sorting out sorting machinery with proximity proteomics
Beverley Wilson, Chloe Flett, Patrick Caswell, et al. use proximity labelling to investigate the Rab4 and Rab11 recycling pathways and identify new machinery that regulates cancer cell migration.
Highlight: journals.biologists.com/jcs/ar
Article: journals.biologists.com/jcs/ar
This article is a @ReviewCommons transfer.
You can find out more about Review Commons and the transfer to affiliate journals including @J_Cell_Sci here: reviewcommons.org/authors/

New Nature article looks at how to end misogyny and inequalities in science

Don’t get mad, get equal: putting an end to misogyny in science
Subtle forms of misogyny attack female leadership and coerce women to conform to conventional gender norms. It’s time to call out these behaviours, say Alison Bentley and Rachael Garrett.
Article available at: nature.com/articles/d41586-023

"One of the paramount lessons of the pandemic is that fresh air matters. Although officials were initially reluctant to acknowledge that the coronavirus was airborne, it soon became clear that the virus spread easily through the air indoors. As the pandemic raged on, experts began urging building operators to crank up their ventilation systems and Americans to keep their windows open. The message: A well-ventilated building could be a bulwark against disease."

nytimes.com/2023/06/17/health/

'Quase um terço das famílias que arrendam casa em Portugal estão em situação de sobrecarga financeira, ou seja, são obrigadas a gastar mais de 40% do seu rendimento disponível para suportar os custos com habitação.'

publico.pt/2023/06/27/economia

Researchers might be willing to take on risky projects if they could be insured against that risk, with wages that didn't depend on the vicissitudes of scientific fortune.

But you can't completely ensure against the failure to get results, because bad luck is indistinguishable from loafing and you need to somehow incentivize effort.

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That's a big 'if'

"Artificial intelligence (AI) is often glibly posed as the answer for services that are already forced to do more with less. Yet the idea that intelligent computers could simply replace humans in medicine is a fantasy. AI tends not to work well in the real world. Complexity proves an obstacle. So far, AI technologies have had little impact on the messy, inherently human world of medicine. But what if AI tools were designed specifically for real-world medicine – with all its organisational, scientific, and economic complexity?"

theguardian.com/commentisfree/

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