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'Impeccable Frenchman though he may have been, the French were never prepared to take Fanon seriously. An Antillais, a psychiatre not a psychanalyste, a non-philosopher in thrall to a simplified existentialism, an alien unable to sympathise with the double bind of Algérie française.'

lrb.co.uk/the-paper/v46/n18/t.

ZipperDB | fully connected neural network that generates scores for individual hexapeptide sequences zipperdb.mbi.ucla.edu/

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#proteomics #prot-other

Palais de Saint-Cloud captures a fleeting moment of elegance, blending nature with architecture. The soft hues and meticulous detail invite viewers to reflect on the beauty of bygone eras. What emotions does this piece evoke for you?
#Art #Rijksmuseum #PalaisdeSaintCloud
rijksmuseum.nl/nl/collectie/RP

'Had we chosen something other than the C57BL/6J mouse as our primary model, the field of metabolism would look very different. A/J mice have shown us that obesity does not always go hand in hand with glucose intolerance (Bachmann et al, 2022; Karimkhanloo et al, 2023), BALB/C mice have revealed the tissue-specific nature of insulin resistance (Nelson et al, 2022), and PWK mice have demonstrated that mice do develop diet-induced NASH akin to humans (Benegiamo et al, 2023). Thus, it is to multi-strain genetic studies, the birthplace of research in mice, that we must return if we are to truly understand the pathogenesis of complex metabolic disease in humans.'

embopress.org/doi/full/10.1038

“In what world can an organisation seriously think it is all right to run a prominent cancer event, bringing together world experts, while also taking sponsorship from a company whose product has caused millions of cancer deaths worldwide? Absolutely shocking.”

theguardian.com/media/2024/sep

'Many scientific journals today seem to function largely as press release vehicles, but Barney's 1965 Nature paper (205:698-699), in which he describes these studies, is an experimentalist's delight.'

nature.com/articles/205698a0

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'When an innkeeper’s​ daughter accused the monk Marinos, a hardened ascetic, of fathering her child, his brethren were appalled. But Marinos, meekly confessing his sin, accepted the punishment of exile and even nursed the infant with milk supplied by shepherds. After several years, the monks readmitted him to the usual monastic routine, along with extra penitential labours. It was not until Marinos died that the monks discovered his secret: he was a biological woman – now honoured liturgically as St Marina.'

lrb.co.uk/the-paper/v46/n18/ba

'Even with myriad uncertainties, it is clear that the virology of the future will be characterized by abundant data. One of the challenges facing biomedicine as a whole will be how handle the enormous amounts of data that will continuously flow into our computer terminals.'

cell.com/cell/fulltext/S0092-8

1/2 Dear fellow Europeans, I am respectfully asking you to consider signing this European Citizen Initiative to institute a billionaire tax. It was invented by leading French economist Thomas Piketty; I read the whole thing, and it is technically excellent. Hit me if you have questions, but please sign it, it is important.

tax-the-rich.eu/

It needs 1 million signatures (currently 300K) and seven countries over their threshold (currently three: Denmark, France, Germany).

Sox9 prevents retinal degeneration and is required for limbal stem cell differentiation in the adult mouse eye biorxiv.org/content/10.1101/20

"To understand JD Vance, you need to meet the 'TheoBros.' These extremely online young Christian men want to end the 19th Amendment, restore public flogging, and make America white again. ...

Many TheoBros, for example, don’t think women belong in the pulpit or the voting booth—and even want to repeal the 19th Amendment."

~ Kiera Butler

#JDVance #Project2025 #WhiteChristianNationalism #theocracy #patriarchy #misogyny #MaleDomination

motherjones.com/politics/2024/

'Reframing microbial mimics as superagonists that are thousands of times better at binding disease-associated autoreactive T cell receptors than self-peptides serves to narrow the search space for relevant sequences in the vast microbial proteome.'

jci.org/articles/view/184046

We love to come up with technology to solve problems that have much simpler solutions.

In this case, some bollards would do the trick. Banning SUVs would be even better.

bloomberg.com/news/articles/20

'Many scientific journals today seem to function largely as press release vehicles, but Barney's 1965 Nature paper (205:698-699), in which he describes these studies, is an experimentalist's delight.'

nature.com/articles/205698a0

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A new report found that the for-profit US healthcare system ranks last among peer nations.

We spend twice as much per capita on healthcare and have the worst health outcomes.

Reminder that Medicare For All would save $450B in health care costs and 68,000 lives per year.

Preventing Inappropriate Signals Pre- and Post-Ligand Perception by a Toggle-Switch Mechanism of ERECTA biorxiv.org/content/10.1101/20

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