The cytidine deaminase APOBEC3A is required for large ribosomal subunit biogenesis https://www.biorxiv.org/content/10.1101/2023.02.20.529126v1?med=mas
@kristinmbranson
thanks for porting Kristin! very interesting.
And happy new year
I found the papers "Scaling Laws for Neural Language Models" (OpenAI, 2020) and "Training Compute-Optimal Large Language Models" (DeepMind, 2022) interesting:
https://arxiv.org/pdf/2001.08361.pdf
https://arxiv.org/pdf/2203.15556.pdf
They do a LOT of experiments training large language models (causal transformers) with varying hyperparameters, in particular model size, shape, batch size, and training data set size over many orders of magnitude. 1/?
RT @teraxurato
New preprint alert!!
We made the first transgenic ants, expressing GCaMP in the antennae (pic), to study how the ant brain encodes social signals. We discovered a core glomerulus in the brain that responds to alarm pheromones.
https://www.biorxiv.org/content/10.1101/2022.12.04.518909v1
[1/XX]
RT @SPBombaci
Colorado State University will host a 10 day short course “Bayesian Models for Ecological Data” from June 5 – June 16, 2023. There is no tuition and travel costs will be partially covered. See https://www.nrel.colostate.edu/projects/bayesian for details and how to apply. Please share widely!
If you don't yet know about the beautiful work done by
@nervous_jessica and @nervous_jesse, today's New York Times has a lovely article about them: https://www.nytimes.com/2022/12/09/science/puzzles-jigsaw-math.html?unlocked_article_code=AAAAAAAAAAAAAAAACEIPuonUktbfqYhlSlUbCibOVtkqqBaLwuDS0q44i2S7LimaUj9diuEcH4jG-1vIYeArQeoP6AmhZY0LNq4zFrs1x_VDPkdpRk70qJbfxs0JfWBvpNPpGz5shsOIVOs2_XqyYzG1I-l1yOXm7xjMeCK9DvykpH4qJwtjpJRnfUj7miBbg_eYTZMmn4V2zvwjBZtlRTwfZSnsv_fgChp2PdTufQiLo0BtGLkfAWeP6Ibav7EQcwxSCkbFT2d_4ws_7tBeP9ARNcXvPm0w3V2AwCkf1F9ciNcGt5o&smid=nytcore-ios-share&referringSource=articleShare
(Also a nice shout out to an algorithm developed by my former PhD student Nick Sharp.)
"Thirteen dubious ways to detect conserved structural RNAs"
W Gao, A Yang, E rivas
Is published and open source
Advertising a job in my group.
thanks for spreading the word
For #women in #science, our work often gets framed in a way that focuses on gender. It’s not a bad thing, but there’s so much more to who we are.
Many of us didn’t set out trying to be “females in science” so much as simply “scientists” doing research we love.
Our contributions are frequently less about shattering glass ceilings, and more about succeeding at institutions that weren’t built by us or for us.
We're thrilled & grateful that our software GSVA has been funded by the Chan Zuckerberg Initiative. This grant will enable giving a much needed upgrade to GSVA that will improve its scalability, robustness and documentation thru this open position https://functionalgenomics.github.io/jobads Please RT!!
JOB ALERT (please reblog) -->
Molecular biologist for zebrafish at Janelia Research Campus, HHMI:
How to migrate from one Mastodon server to another without losing followers:
1. Sign up on new server
2. On NEW server: Go to Account -> Moving FROM another account
3. Enter old account's handle
4. On OLD server: Go to Account -> Moving TO another account
5. Enter new account's handle and submit
My first toot.
I'm eligible to apply for a diversity supplement for my NIH grant (https://grants.nih.gov/grants/guide/pa-files/PA-21-071.html). If you fall into an underrepresented group, are interested in building computational/ML methods for genomics, and are looking for a postdoc next year, get in touch! (note: in computing, women are underrepresented!) Please boost
I wrote a quick introduction to Mastodon, meant for beginners and with a particular emphasis on scientists. Feel free to share with your community outside of Mastodon!
https://giorgio.gilest.ro/2022/11/05/mastodon-an-introduction-for-beginners-and-for-scientists/
I'd better do another #introduction with the new influx of folx into #fediverse.
Hi, I'm Dave. I'm a staff #Scientist at a biomedical Research Institute in #London, #UK
I'm a #StructuralBiologist by training. I help run a group that studies #Kinase #signaling in human #health and #disease.
I do #Crystallography #CryoEM #Biophysics #DrugDesign and #Glycobiology. #Science
In my course MCB111 "mathematics in biology", we just learned about Hopfield networks and the Hebbian learning. Can anyone give a critical reading of this paper for us?
On theoretical neural circuits for counting, and their biological implementation in the #Drosophila brain:
"Our second model uses anti-Hebbian plasticity and only tracks frequencies within four count categories (“1-2-3-many”) ... we show that an implementation of the “1-2-3-many” count sketch exists in the insect mushroom body."
From: "A neural theory for counting memories" by Dasgupta et al. 2022 https://www.nature.com/articles/s41467-022-33577-2
We are looking for postdocs! (1) To study how brainwide neuronal activity supports diverse behaviors (w Kenneth Harris); (2) To relate the activity of a neuron to its pre- and postsynaptic neurons across cortex (w Alipasha Vaziri and Federico Rossi). https://tinyurl.com/CortexlabPostdoc
@mcsymbiont yeah the concept of the server is still alien to me. I noticed you are in a different one than me.
Happy to find you here too. Let's keep in touch.
computational biologist. algorithms for genomics. worried about sustainability from personal 2 country(ies) 2 planet.