DaveFinlayTCD @finlayd@qoto.org
We are an Immunometabolism research group that studies how nutrients and metabolism affect immune cell function at #TrinityCollegeDublin👨🔬 Love #NK_cells, #Dendritic_cells and #T_cells but can be easily convinced to talk at length about metabolism in any immune cell 😄. Twitter handle @DavidFinlayTCD
Joined Nov 2022
RT @janeohlmeyer
Signed, sealed, delivered! Our open letter to @SimonHarrisTD with 1800+ signatures was delivered to @DeptofFHed today where we had a very constructive meeting with Minister. Now to next steps @OireachtasNews, let's make Ireland the best place to do research #LoveIrishResearch
IDO-Gal3 reduces the severity of symptoms in mice with established osteoarthritis.
They also show anti-inflammatory effects in skin inflammation and that IDO-Gal3 averts and inhibits periodontal disease progression. (4/5)
Using a mechanical overloading osteoarthritis mouse model, mice were treated weekly with intra-articular IDO-Gal3 injections.
You can clearly see the retention of Gal3-IDO in the joint. (3/5)
Key advance:
Generating an IDO-Gal3 fusion protein.
Gal3 binds to fly and in the extracellular matrix (ECM) of tissues, anchoring IDO in place at the site of inflammation - very clever IMHO. (2/5)
Interesting analysis of manuscript retraction data, 2010-12 vs 2017-19:
-Increase in # of retracted papers
-Change in geographical origins.
😬
Data in figures shows groups of urban areas between which at least 2 retracted articles were co-authored.
https://dapp.orvium.io/deposits/6442fee5c93d17c257de17d2/view
We are an Immunometabolism research group that studies how nutrients and metabolism affect immune cell function at #TrinityCollegeDublin👨🔬 Love #NK_cells, #Dendritic_cells and #T_cells but can be easily convinced to talk at length about metabolism in any immune cell 😄. Twitter handle @DavidFinlayTCD
Joined Nov 2022
