The best, deepest, dialogues they ever had on Star Trek: Voyager.
Janeway: Let me ask you something. If you were something other than a human being, if you were a different kind of animal... If you were a small bird, a sparrow - what would your world be like?
da Vinci: I should make my home in a tree, in the branch of an elm. I should hunt insects for food, straw for my nest, and in the springtime, I should sing for a companion.
Janeway: And you would know nothing of the politics of Florence - the cutting of marble or mathematics.
da Vinci: Of course not.
Janeway: But why not?
da Vinci: My mind would be too small.
Janeway: As a sparrow, your mind would be too small, even with the best of teachers?
da Vinci: If Aristotle himself were to perch on my branch and lecture till he... fell off from exhaustion - still the limits of my mind would prevent me from understanding.
Janeway: And as a man, can you accept that there may be certain realities beyond the limits of your comprehension?
da Vinci: If I could not accept that... then I would be a fool.
@nerthos I wouldnt go that far, but it was one of the good ones. TNG will always be best IMO :)
Neither will beat Babylon 5 when it comes to philosophical and moral content though.