Moderate Elevation of Homocysteine Induces Endothelial Dysfunction through Adaptive UPR Activation and Metabolic Rewiring. https://www.preprints.org/manuscript/202309.0215/v1 #Morpholino
The gastropod Lottia peitaihoensis as a model to study the body patterning of trochophore larvae. https://onlinelibrary.wiley.com/doi/10.1111/ede.12456 #Morpholino
Sulindac selectively induces autophagic apoptosis of GABAergic neurons and alters motor behaviour in zebrafish. https://www.nature.com/articles/s41467-023-41114-y #Morpholino
Characterization of Msantd4 Gene in the Development of Xenopus Laevis. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4559111 #Morpholino
Endosomal Escape Vehicle–Oligonucleotide Conjugates for the Targeted Upregulation and
Downregulation of Gene Expression. https://entradatx.com/documents/presentations/entrada_streeter_eev-pmo-to-up-&-downregulate-gene-expression_aps-2023.pdf #Morpholino
Disruption of fos causes craniofacial anomalies in developing zebrafish. https://www.frontiersin.org/articles/10.3389/fcell.2023.1141893/full #Morpholino
DMD antisense oligonucleotide mediated exon skipping efficiency correlates with flanking intron retention time and target position within the exon. https://www.tandfonline.com/doi/full/10.1080/15476286.2023.2254041 #Morpholino
Apical size and deltaA expression predict adult neural stem cell decisions along lineage progression. https://www.science.org/doi/10.1126/sciadv.adg7519 #Morpholino
Downregulation of Zebrafish Cytosolic Sialidase Neu3.2 Affects Skeletal Muscle Development. https://www.mdpi.com/1422-0067/24/17/13578 #Morpholino
YTHDF2-mediated regulations bifurcate BHPF-induced programmed cell deaths. https://academic.oup.com/nsr/advance-article/doi/10.1093/nsr/nwad227/7252931 #Morpholino
Zbtb16 mediates a switch between Fgf signalling regimes in the developing hindbrain. https://journals.biologists.com/dev/article/doi/10.1242/dev.201319/326583/Zbtb16-mediates-a-switch-between-Fgf-signalling #Morpholino
Knockdown of klotho Leads to Cell Movement Impairment during Zebrafish Gastrulation. https://www.mdpi.com/2410-3888/8/9/440 #Morpholino
DRAM1 confers resistance to Salmonella infection. https://www.tandfonline.com/doi/full/10.1080/27694127.2023.2242715 #Morpholino
Rare variants in CAPN2 increase risk for isolated hypoplastic left heart syndrome. https://www.cell.com/cms/10.1016/j.xhgg.2023.100232/attachment/21afb3a1-a16f-418d-9d4a-525c460d1bd8/mmc1.pdf #Morpholino
Loss of Mtm1 causes cholestatic liver disease in a model of X-linked myotubular myopathy.
https://www.jci.org/articles/view/166275 #Morpholino
(poster) The efficacy of vitamin B6 derivatives in reliving epileptic-like
anomalies in PNPO knockdown zebrafish. https://nckur.lib.ncku.edu.tw/retrieve/225775/%E7%AC%AC%E4%BA%94%E5%B1%86%E5%9C%8B%E9%9A%9B%E7%B6%AD%E7%94%9F%E7%B4%A0%E6%9C%83%E8%AD%B0%20%E6%B5%B7%E5%A0%B1.pdf #Morpholino
Paracrine regulation of neural crest EMT by placodal MMP28. https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002261 #Morpholino
“Plod2” a Lysyl Hydroxylase Required for HSC Specification. https://www.exphem.org/article/S0301-472X(23)01483-2/pdf #Morpholino
Extracellular Pgk1 interacts neural membrane protein enolase-2 to improve the neurite outgrowth of motor neurons. https://www.nature.com/articles/s42003-023-05223-0 #Morpholino
Ontogenetically distinct neutrophils differ in function and transcriptional profile in zebrafish. https://www.nature.com/articles/s41467-023-40662-7 #Morpholino
It's been all Morpholinos all the time for about 23 years. I'm a scientist with Gene Tools LLC.