@valleyforge About as powerful is not as powerful. It may have the velocity advantage, but not the stopping power.
I would trust my life against a bear with a 45ACP bullet, but not a 40SW. Which is something realistic I have to consider everytime I set foot outside.
However, I believe 40SW has a serious advantage in times of ammunition shortage, because no one is buying it, and it's still available everywhere for relatively cheap.