🇳🇱
Paranoid Schizophrenia is a hell of a hard disease to deal with when your friend gets it.
My friend developed it a few years ago when we were working on a company together. He was about at the age of onset.
I have dealt with a lot of diseases among my friends including drug addiction, depression, anxiety, but of them all Schizofrenia is the hardest because even if they want to they cant understand or listen to reason, so no words or even actions can be effective most of the time.
Its a hell of a disease and worse yet him as someone who is suffering with it has lost almost all of his friends and it isnt helping him mental health or ability to correct the problem.
@freemo it is a cruel disease yet I find it so interesting. From a neurobiological point of view, loads of stuff seems to be implicated in this: metalloproteases such as MMP-9, when overexpressed, can degrade the extracellular matrix of inhibitory GABAergic neurons so that the neural network is altered, leading to schizophrenia-like symptoms. But MMP-9 is just one molecule among many others: just on the top of my head I remember Reelin, MMP-2, semaphorins. Basically we don't know shit about this (and this of course makes it more interesting)
