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Paranoid Schizophrenia is a hell of a hard disease to deal with when your friend gets it.

My friend developed it a few years ago when we were working on a company together. He was about at the age of onset.

I have dealt with a lot of diseases among my friends including drug addiction, depression, anxiety, but of them all Schizofrenia is the hardest because even if they want to they cant understand or listen to reason, so no words or even actions can be effective most of the time.

Its a hell of a disease and worse yet him as someone who is suffering with it has lost almost all of his friends and it isnt helping him mental health or ability to correct the problem.

@freemo I have a friend with that too. They fried the poor guys brain on head meds and his brain is swimming in so much chemical soup now he has the IQ of a child.

@Wetrix Im not sure if the meds fried him or its just the disease. To be honest the disease makes it very hard for most people to grow intellectually because off the meds they are completely incapable of recognizing what is real, and on the meds they are so tired they dont really have the motivation to learn or apply themselves.

My guess is your friend wasnt fried by the medicine, its just the consequence of the damn disease. In all liklihood he is probably better on the meds than off.

@freemo he got after he had a mental breakdown. It was all downhill from there. I don't know when exactly it started but they used him like a lab rat back then along with millions of other people.

This was just when riddlen, Prozac & frehzan etc all these head meds had just hit the market and they didn't know the long term or short term FX of them and just pumped people like him full of them and fried his brain. 😕

@Wetrix I dont know the exact situation, obviously there is a point where doctors could be reckless in their dosing. But the truth is schizophrenics tend to have a very poor quality of life if you cant find the correct dosage for them. So they may have just been desperate to find a solution and had to go to riskier doses or medication.

I think what would be more telling here is if they tried less risky intervention first, known drugs that were safe and only moved on to riskier doses or drugs when the more conventional solutions failed.

@freemo true, I just felt like I seen him used as a medical lab rat and them shoveling any pills they could down down his throat.

Obviously I have a bias because I'm his friend to this day.

Before the breakdown and all the chemical soup he's on he was a normal happy and intelligent guy. So sad to see what he is now.

He walks around in a medical induced haze, one step away from being a pill zombie. 💊

@Wetrix yea but at what age was this.. If it was in his 20's or earlier then the happy intelligent man you used to see was likely just because it was before the onset of his disease, and wasnt ruined so much by the pills as it was by the disease. When this thing finally kicks in they change drastically and perminately and the change appears rather sudden..

@Wetrix

Prozac is not used to treat schizophrenia, it's actually not recommended as it may increase symptoms. Only in specific situations, when you suffer both from schizophrenia and depression.

@freemo

@kravietz

Yea agreed. but it is very common because the meds to treat the schizophrenia tend to make people feel unmotivated and can often give people depression-like symptoms. so it isnt that uncommon to add on prozac to counter any impression that can be caused by other medications. Obviously the fewer meds the better so it shouldnt be a first-line drug as it wont even treat the schizofrenia itself.

@Wetrix

@freemo Its worse when one gets misdiagnosed with bipolar disorder, because that's the trend of the day back then. So treatment was inadequate to say the least and things got worse. Its only later she got diagnosed with being a schizo, but by that time we'd broken up ages ago. She offed herself 3 years ago. I still think about her from time to time.

@freemo it is a cruel disease yet I find it so interesting. From a neurobiological point of view, loads of stuff seems to be implicated in this: metalloproteases such as MMP-9, when overexpressed, can degrade the extracellular matrix of inhibitory GABAergic neurons so that the neural network is altered, leading to schizophrenia-like symptoms. But MMP-9 is just one molecule among many others: just on the top of my head I remember Reelin, MMP-2, semaphorins. Basically we don't know shit about this (and this of course makes it more interesting)

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