Real-time imaging of enteric pathogens invading a gut-on-a-chip and evaluating how peristalsis facilitates this. By research from @PasteurEdu
#organonchip #mechanobiology
Hello everyone - I am Hugo Mouquet - PhD, molecular #immunologist & head of the humoral immunology lab @ Institut Pasteur - Our lab investigates #antibodies and B-cell responses to viral pathogens in humans | #HIV, #hepatitis #viruses, #SARSCoV2, #chikungunya & more...
Now in #Science magazine (@sciencemagazine)
Katherine Freitas, Julia Belk, Ansu Satpathy, Crystal Mackall, & colleagues use #CRISPR screen to identify MED12 & CCNC as key regulators of human #TCell activation & function. Inactivation in #CART cells leads to increased T cell expansion, #metabolic fitness, & #tumor control!
bit.ly/Sci_abn5647
Be sure to also check out the accompanying Perspective by Caitlin Zebley & Ben Youngblood:
#introduction I am an #immunologist at the #universityoftoronto. I study how our #mucosal immune system can influence our health, especially brain health. I love constructive discussions about science and how to make #academia a better place for everyone. I love #cooking, #gardening, #singing, #canoeing and learning from my 2 sons. Oh and my 3 @Cats too.
Celiac disease | Mucosal immunology | iPSCs, Intestinal Organoids, T cells & organs-on-chips🔬
PhD-candidate Genetics dept. 🧬 University Medical Center Groningen,
the Netherlands